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Pituitary tumors and pregnancy: the interplay between a pathologic condition and a physiologic status

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An Erratum to this article was published on 01 May 2014

Abstract

Pregnancy is becoming a relatively common event in patients with pituitary tumors (PT), due to the increasing availability of medical treatments, which control pituitary diseases associated with the development of PT. However, the presence of PT and its treatment may be a disturbing factor for pregnancy, and pregnancy significantly influences the course and the management of PT. This review summarizes the knowledge about the management of PT during pregnancy and the occurrence of pregnancy in patients with pre-existent PT, focusing on secreting PT characterized by hormonal excess and on clinically non-functioning PT often associated to hormone deficiency, which configure the hypopituitaric syndrome.

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Conflict of interest

AC has been principal investigator of research studies from Novartis, Ipsen, Pfizer and Lilly, has received research grants from Ferring, Lilly, Ipsen, Merck-Serono, Novartis, Novo-Nordisk and Pfizer, has been occasional consultant for Novartis, Ipsen and Pfizer, and has received fees and honoraria from Ipsen, Novartis, and Pfizer. RP has been principal investigator of research studies from Novartis, has received research grants from Novartis, Pfizer, Viropharma and IBSA, has been occasional consultant for Novartis, Ipsen, Pfizer, Viropharma, Ferring, Italfarmaco and received fees and honoraria for presentations from Novartis. MCDM, RSA, CA, LFSG, AC, MDL, GDP, GL have nothing to disclose.

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  1. Section of Endocrinology, Department of Clinical Medicine and Surgery, “Federico II” University, Naples, Italy

    Rosario Pivonello, Maria Cristina De Martino, Renata S. Auriemma, Ludovica F. S. Grasso, Alessia Cozzolino, Monica De Leo, Annamaria Colao & Gaetano Lombardi

  2. Section of Gynaecology, Department of Neurosciences, Reproductive and Odontostomatologic Sciences, “Federico II” University, Naples, Italy

    Carlo Alviggi & Giuseppe De Placido

  3. Department of Molecular and Clinical Endocrinology and Oncology , “Federico II” University, Via S. Pansini 5, 80131, Naples, Italy

    Rosario Pivonello

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Pivonello, R., De Martino, M.C., Auriemma, R.S. et al. Pituitary tumors and pregnancy: the interplay between a pathologic condition and a physiologic status. J Endocrinol Invest 37, 99–112 (2014). https://doi.org/10.1007/s40618-013-0019-8

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