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Elecsys® AMH Assay: A Review in Anti-Müllerian Hormone Quantification and Assessment of Ovarian Reserve

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Abstract

The Elecsys® AMH assay is an in vitro, fully automated assay indicated for the quantification of anti-Müllerian hormone (AMH) in human serum/lithium-plasma, which (in conjunction with other clinical and laboratory findings) can help to determine ovarian reserve. The assay is highly sensitive and precise, with a broad linear range, and correlates well with manual AMH assays and transvaginal sonographic assessment of antral follicle count, but has the benefit of being less variable. The Elecsys® AMH assay also has a shorter testing time than some other AMH assays and was shown to provide a reproducible measure of ovarian reserve in women of reproductive age in a large prospective cohort study, demonstrating its usefulness in this setting.

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Disclosure

The preparation of this review was not supported by any external funding. During the peer review process, the manufacturer of the assay under review was offered an opportunity to comment on this article. Changes resulting from comments received were made by the author on the basis of scientific and editorial merit. Emma Deeks is a salaried employee of Adis/Springer.

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    Emma D. Deeks

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  1. Emma D. Deeks
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Correspondence to Emma D. Deeks.

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The manuscript was reviewed by: C. Peluso, Department of Collective Health, Division of Reproductive Health and Population Genetics, Faculdade de Medicina do ABC, Santo Andre, Brazil; N .P. Polyzos, Center for Reproductive Medicine, Universitair Ziekenhuis Brussel and Vrije Universiteit Brussel, Brussels, Belgium.

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Deeks, E.D. Elecsys® AMH Assay: A Review in Anti-Müllerian Hormone Quantification and Assessment of Ovarian Reserve. Mol Diagn Ther 19, 245–249 (2015). https://doi.org/10.1007/s40291-015-0156-1

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  • DOI: https://doi.org/10.1007/s40291-015-0156-1

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