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The Microbiome and Atopic Dermatitis: A Review

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Abstract

The microbiome is defined as the sum of microbes, their genomes, and interactions in a given ecological niche. Atopic dermatitis is a multifactorial chronic inflammatory skin disease leading to dryness and itchiness of the skin. It is often associated with comorbidities such as allergic rhinoconjunctivitis and asthma. Today, culture-free techniques have been established to define microbes and their genomes that may be both detrimental and beneficial for their host. There are signs that microbes, both on skin and in the gut, may influence the course of atopic dermatitis. Antiseptic treatment has been used for decades, however now, with the help of traditional culture-based methods and modern metagenomics, we are beginning to understand that targeted treatment of dysbiosis may possibly become part of an integrated therapy plan in the future.

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Authors and Affiliations

  1. Department of Dermatology, University Hospital Jena, Erfurter Straße 35, 07740, Jena, Germany

    Anna Pothmann, Tanja Illing, Cornelia Wiegand & Peter Elsner

  2. Private Dermatology Practice, Erfurt, Germany

    Albert A. Hartmann

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Pothmann, A., Illing, T., Wiegand, C. et al. The Microbiome and Atopic Dermatitis: A Review. Am J Clin Dermatol 20, 749–761 (2019). https://doi.org/10.1007/s40257-019-00467-1

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