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Synthesis of 1-((5-oxo-4,5-Dihydro-1,3,4-oxadiazol-2-yl)methyl)-1H-1,2,4-triazole-3-carboxylic Acid-Application of Antibacterial activity

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Abstract

Synthesis of 1-((5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl) methyl)-1H-1,2,4-triazole-3-carboxylic acid was accomplished starting with the commercially available 1,2,4-triazole-3-carboxylic acid. The conversion of hydrazide and carbon dioxide to 1,3,4-oxadiazole has been explained. Antibacterial activity also studied for some synthesized compounds.

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Authors and Affiliations

  1. Department of Engineering Chemistry, Andhra University, Visakhapatnam, Andhra Pradesh, India

    Manuri Brahmayya & Battula Venkateswara Rao

  2. Department of Chemical Engineering, National Chung Hsing University, Taichung, Taiwan

    Manuri Brahmayya

  3. Department of Environmental Engineering Safety and Health, HungKuang University, Shalu District, Taichung, Taiwan, ROC

    Manuri Brahmayya & Huan-Jung Fan

  4. Department of Organic Chemistry and FDW, Andhra University, Visakhapatnam, India

    Dasi Samsonu

  5. Department of Physics, Advanced Functional Materials Research Centre, K L University, Guntur, Andhra Pradesh, India

    Alaparthi Venkateswara Rao

  6. Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan, ROC

    Nelli Srinivasa Rao

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  1. Manuri Brahmayya
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  2. Dasi Samsonu
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  3. Alaparthi Venkateswara Rao
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  4. Nelli Srinivasa Rao
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  5. Battula Venkateswara Rao
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  6. Huan-Jung Fan
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Correspondence to Manuri Brahmayya.

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Brahmayya, M., Samsonu, D., Venkateswara Rao, A. et al. Synthesis of 1-((5-oxo-4,5-Dihydro-1,3,4-oxadiazol-2-yl)methyl)-1H-1,2,4-triazole-3-carboxylic Acid-Application of Antibacterial activity. Proc. Natl. Acad. Sci., India, Sect. A Phys. Sci. 89, 621–627 (2019). https://doi.org/10.1007/s40010-018-0507-5

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  • DOI: https://doi.org/10.1007/s40010-018-0507-5

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