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Anti-Ma2 encephalitis presenting with hearing loss, hypersomnolence and confusion: a case report

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Abbreviations

AFP:

Alpha fetoprotein

CNS:

Central nervous system

CSF:

Cerebrospinal fluid

FDG-PET:

Fluorine-18-fluorodeoxyglucose positron emission tomography

hCG:

Human chorionic gonadotropin

IgG:

Immunoglobulin G

MSLT:

Multiple sleep latency test

PNS:

Paraneoplastic syndrome

SOREM:

Sleep onset rapid eye movement

WBC:

White blood cells

μl:

Microliters

References

  1. Hoffmann LA, Jarius S, Pellkofer HL, Schueller M, Krumbholz M, Koenig F, Johannis W, la Fougere C, Newman T, Vincent A, Voltz R (2008) Anti-Ma and anti-Ta associated paraneoplastic neurological syndromes: 22 newly diagnosed patients and review of previous cases. J Neurol Neurosurg Psychiatry 79(7):767–773. https://doi.org/10.1136/jnnp.2007.118588 (Epub 2008 Jan 25 PMID: 18223018)

    Article  CAS  PubMed  Google Scholar 

  2. Bosemani T, Huisman TA, Poretti A (2014) Anti-Ma2-associated paraneoplastic encephalitis in a male adolescent with mediastinal seminoma. Pediatr Neurol 50(4):433–434. https://doi.org/10.1016/j.pediatrneurol.2013.12.020 (Epub 2014 Jan 1 PMID: 24630289)

    Article  PubMed  Google Scholar 

  3. Fransesc G et al (2021) Updated diagnostic criteria for paraneoplastic neurologic syndromes. Neurol Neurimmunol Neuroinflamm 8:e1014. https://doi.org/10.1212/NXI.0000000000001014

    Article  Google Scholar 

  4. Souza PV, Bortholin T, Pinto WB, Santos AJ (2017) Progressive hearing loss and cerebellar ataxia in anti-Ma2-associated autoimmune encephalitis. Arq Neuropsiquiatr 75(1):74–75. https://doi.org/10.1590/0004-282X20160169 (PMID: 28099568)

    Article  PubMed  Google Scholar 

  5. Overeem S, Dalmau J, Bataller L, Nishino S, Mignot E, Verschuuren J, Lammers GJ (2004) Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis. Neurology 62(1):138–140. https://doi.org/10.1212/01.wnl.0000101718.92619.67.PMID:14718718;PMCID:PMC2574537

    Article  CAS  PubMed  Google Scholar 

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Serrien, A., Van Der Meersch, M., Vanhoenacker, P. et al. Anti-Ma2 encephalitis presenting with hearing loss, hypersomnolence and confusion: a case report. Acta Neurol Belg 122, 1123–1125 (2022). https://doi.org/10.1007/s13760-022-01933-0

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