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Giant retroperitoneal myolipoma mimicking liposarcoma: report of a resected case and review of the literature

  • Case report - Pathology
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Abstract

Myolipomas are rare tumors that are often difficult to differentiate from liposarcoma. Herein, we report a case of resected giant myolipoma preoperatively diagnosed as liposarcoma. A 63-year-old woman was suspected of having a large retroperitoneal liposarcoma on October 202X. The patient was referred to our department for tumor resection and a histological diagnosis. After consultation with the urology, obstetric and gynecology, and vascular surgery departments, tumor resection was planned, including the potential resection of other organs. Intraoperative findings revealed a large, elastic, soft tumor with a smooth surface and a capsule occupying the entire abdominal cavity. The tumor was adherent to the stomach, left colon, and uterine adnexa, and no invasion was observed. The tumor was completely resected, and organ resection was not necessary. The tumor was 40 cm in diameter and 4.0 kg in weight. Pathological examination and immunostaining confirmed a diagnosis of myolipoma. The patient’s postoperative course was uneventful, and she was discharged on postoperative day 10 with no complications. Twelve months after surgery, the patient was doing well. To the best of our knowledge, we report a complete resection of the largest retroperitoneal myolipoma reported to date. Physicians should consider surgery, even for suspected large sarcomas that may be difficult to resect completely.

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Data availability

The data supporting the findings of this study are available from the corresponding author upon reasonable request.

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Acknowledgements

We appreciate all the individuals who collaborated in this research.

Funding

The authors declare that there was no financial support provided for this study.

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Authors and Affiliations

  1. Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan

    Kosuke Mori, Takamichi Igarashi, Miki Ito, Yasuhiro Nagaoka, Chitaru Takeshita, Naoya Takeda, Toru Watanabe, Isaku Yoshioka & Tsutomu Fujii

  2. Department of Diagnostic Pathology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Toyama, 930-0194, Japan

    Akira Noguchi & Kenichi Hirabayashi

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  1. Kosuke Mori
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  2. Takamichi Igarashi
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Contributions

KM reported the case and wrote the manuscript. KM, TI, MI, YN, CT, NT, TW, IY, and TF were involved in treating the patient. AN and KH were involved in the pathological diagnosis. TI and TF participated in revising the manuscript critically. All authors declare that they contributed to this article and that they have read and approved the final manuscript.

Corresponding author

Correspondence to Tsutomu Fujii.

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Written informed consent was obtained from the patient for the publication of this case report and the accompanying images.

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Mori, K., Igarashi, T., Noguchi, A. et al. Giant retroperitoneal myolipoma mimicking liposarcoma: report of a resected case and review of the literature. Int Canc Conf J 13, 144–152 (2024). https://doi.org/10.1007/s13691-024-00655-9

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  • DOI: https://doi.org/10.1007/s13691-024-00655-9

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