Abstract
Hepatobiliary cystoadenoma is a rare cystic tumor of the liver that can undergo malignant change and become lethal. Accurate diagnosis of such lesions, even though not always possible, is of importance as the management is totally different from that of other nonneoplastic cysts. We report a case of a 60-year-old woman with aspecific symptoms, which was diagnosed using ultrasound scan and CT scan and treated with hepatic resection, and review the main features of this tumor.
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Yu FC, Chen JH, Yang KC, Wu CC, Chou YY (2008) Hepatobiliary cystoadenoma: report of two cases. J Gastrointestin Liver Dis 17:203–206
Keen W (1892) On resection of the liver, especially for hepatic tumours. Boston Med Surg J 126:405–409
Barabino M, Leone S, Dapri G, Marsetti M, Ghislandi R, Opocher E (2004) Hepatobiliary cystoadenoma: diagnostyic uncertainty. HPB (Oxford) 6:52–54
Buetow PC, Buck JL, Pantongrag-Brown L, Ros PR, Devaney K, Goodman ZD, Cruess DF (1995) Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. Radiology 196:805–810
Pinson CW, Munson JL, Rossi RL et al (1989) Enucleation ofintrahepatic biliary cystadenomas. Surg Gynecol Obstet 168:534–537
Ishak KG, Willis GW, Cummins SD, Bullock AA (1977) Biliary cystadenoma and cystadenocarcinoma: report of 14 cases and review of the literature. Cancer 39:322–338
Choi BI, Lim JH, Han MC, Lee DH, Kim SH, Kim YI, Kim CW (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61
Woods GL (1981) Biliary cystadenocarcinoma: case report of hepatic malignancy originating in benign cystadenoma. Cancer 47:2936–2940
Ramacciato G, Nigri GR, D’Angelo F, Aurello P, Bellagamba R, Colarossi C, Pilozzi E, Del Gaudio M (2006) Emergency laparotomy for misdiagnosed biliary cystadenoma originating from caudate lobe. World J Surg Oncol 4:76
Farrell L (2004) Benign and malignant tumours of the liver. In: Odze RD, Goldblum JR, Crawford JM (eds) Surgical Pathology of the GI Tract, Liver, Biliary Tract, Pancreas. Saunders, Philadelphia pp 1015–1016
Devaney K, Goodman ZD, Ishak KG (1994) Hepatobiliary cystadenoma and cystadenocarcinoma: a light microscopic and immunohistochemical study of 70 patients. Am J Surg Pathol 18:1078–1091
Cruickshank AH, Sparshott SM (1971) Malignancy in natural and experimental hepatic cysts: experiments with aflotoxin in rats and the malignant transformation of cysts in human livers. J Pathol 104:185–190
Akwari OE, Tucker A, Seigler HF, Itani KM (1990) Hepatobiliary cystadenoma with mesenchymal stroma. Ann Surg 211:18–27
Devine P, Ucci AA (1985) Biliary cystadenocarcinoma arising in a congenital cyst. Hum Pathol 16:92–94
Thomas KT, Welch D, Trueblood A, Sulur P, Wise P, Gorden DL, Chari RS, Wright JK Jr, Washington K, Pinson CW (2005) Effective treatment of biliary cystadenoma. Ann Surg 241:769–773
Lee JH, Chen DR, Pang SC, Lai YS (1996) Mucinous biliary cystadenoma with mesenchymal stroma: expressions of CA 19-9 and carcinoembryonic antigen in serum and cystic fluid. J Gastroenterol 31:732–736
Koffron A, Rao S, Ferrario M, Abecassis M (2004) Intrahepatic biliary cystadenoma: role of cyst fluid analysis and surgical management in the laparoscopic era. Surgery 136:926–936
Dixon E, Sutherland F, Burak K, McKinnon G, May G (2001) Cystadenoma of the liver without mesenchymal stroma in a female following hormonal therapy for acne. HPB (Oxford) 3:183–186
Matsumoto S, Miyake H, Mori H (1997) Case report: biliary cystadenoma with mucin-secretion mimicking a simple hepatic cyst. Clin Radiol 52:316–318
Teoh AY, Ng SS, Lee KF, Lai PB (2006) Biliary cystadenoma and other complicated cystic lesions of the liver: diagnostic and therapeutic challenges. World J Surg 30:1560–1566
Lewin M, Mourra N, Honigman I, Fléjou JF, Parc R, Arrivé L, Tubiana JM (2006) Assessment of MRI and MRCP in diagnosis of biliary cystadenoma and cystadenocarcinoma. Eur Radiol 16:407–413
Vogt DP, Henderson JM, Chmielewski E (2005) Cystadenoma and cystadenocarcinoma of the liver: a single center experience. J Am Coll Surg 200:727–733
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Navarra, G., Iusco, D.R., Bonomi, S. et al. Hepatobiliary cystoadenoma: a wolf in sheep’s clothing. Updates Surg 62, 203–206 (2010). https://doi.org/10.1007/s13304-010-0035-6
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DOI: https://doi.org/10.1007/s13304-010-0035-6