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Glycoside hydrolases in the biodegradation of lignocellulosic biomass

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Abstract

Lignocellulose is a plentiful and intricate biomass substance made up of cellulose, hemicellulose, and lignin. Cellulose and hemicellulose are polysaccharides characterized by different compositions and degrees of polymerization. As renewable resources, their applications are eco-friendly and can help reduce reliance on petrochemical resources. This review aims to illustrate cellulose, hemicellulose, and their structures and hydrolytic enzymes. To obtain desirable enzyme sources for the high hydrolysis of lignocellulose, highly stable, efficient and thermophilic enzyme sources, and new technologies, such as rational design and machine learning, have been introduced in detail. Generally, the efficient biodegradation of abundant natural biomass into fermentable sugars or other intermediates has great potential in practical applications.

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Funding

This work was financially supported by the National Natural Science Foundation (No. 21878160) and Key R&D Plan Cultivation Project of Huaiyin Institute of Technology (No. 22HGZ001).

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H. L, M. X and X. N drafted the manuscript, H. L, Z. T and X. Y revised the manuscript, H. S, X. L and T. W administered the work, drafted the manuscript and critically revised the manuscript.

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Correspondence to Hao Shi, Xun Li or Tao Wang.

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Lu, H., Xue, M., Nie, X. et al. Glycoside hydrolases in the biodegradation of lignocellulosic biomass. 3 Biotech 13, 402 (2023). https://doi.org/10.1007/s13205-023-03819-1

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  • DOI: https://doi.org/10.1007/s13205-023-03819-1

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