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Antibacterial activity and photocatalytic dye degradation of copper oxide nanoparticles (CuONPs) using Justicia gendarussa

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Abstract

The present study explores a facile, non-toxic, and ecofriendly synthesis of biomolecules functionalized copper oxide nanoparticles (CuONPs) using Justicia gendarussa (J.gendarussa) leaf extract for the first time. The leaf extract was used as a potential capping and stabilising agent for the reduction of copper ions to CuONPs.The structure, morphology, elemental composition, and stability of the synthesised CuONPs were characterised using UV, FTIR, FESEM–EDX, TEM, and DLS analyses. The surface plasmon resonance (SPR) of the CuONPs exhibited a strong characteristic band at 340 nm. The capping of biomolecules in the synthesised CuONPs was confirmed by FTIR. The SEM and TEM analyses showed that the synthesised CuONPs were nano flower in shape and the size ranged between 10 and 15 nm. The existence of elements, Cu (56.70) and O (43.30), was confirmed by EDX analysis. The functionalised biomolecules of CuONPs exhibited bactericidal activity against both Gram negative and Gram positive pathogens. The photocatalytic ability of the CuONPs was tested against the textile dye, methylene blue (MB) using natural irradiation method. The results of this study revealed that the synthesised CuONPs proved to be an interesting candidate in wastewater treatment and biomedical applications.

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Acknowledgements

The authors would like to thank IGPRED (www.igpred.com) for providing insight and expertise on the research topic and for the assistance that greatly improved the manuscript.

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Authors and Affiliations

  1. Department of Biotechnology, Hindusthan College of Arts and Science, Coimbatore, Tamil Nadu, 641028, India

    Seerangaraj Vasantharaj, Pooja Shivakumar & Palanisamy Senthilkumar

  2. CORX Lifesciences and Pharmaceutical Private Limited, Tiruchirappalli, Tamil Nadu, India

    Selvam Sathiyavimal

  3. School of Energy Environment and Natural Resources, Madurai Kamaraj University, Madurai, India

    Seerangaraj Vijayaram

  4. Biological Material Laboratory, CSIR-Central Leather Research Institute (CLRI), Chennai, Tamil Nadu, 600020, India

    Muthiah Shanmugavel

  5. College of Medical and Health Science, Asia University, Taichung, Taiwan

    Arivalagan Pugazhendhi

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  1. Seerangaraj Vasantharaj
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  2. Pooja Shivakumar
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  4. Palanisamy Senthilkumar
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Vasantharaj, S., Shivakumar, P., Sathiyavimal, S. et al. Antibacterial activity and photocatalytic dye degradation of copper oxide nanoparticles (CuONPs) using Justicia gendarussa. Appl Nanosci 13, 2295–2302 (2023). https://doi.org/10.1007/s13204-021-01939-9

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