Abstract
Somatostatin receptor (SSTR)-based imaging and therapy has emerged as well-established modality in neuroendocrine tumors. However, its role in inflammation imaging is still evolving. We present a 48-year-old male with metastatic neuroendocrine tumor who underwent lutetium-177-based somatostatin receptor-based therapy. The post-therapy scan showed a focal tracer uptake in the left calf muscle in addition to the expected tracer uptake at the primary and metastatic sites. Further, cross-sectional imaging and biochemical investigations revealed peripheral vascular disease (PVD). The incidental tracer uptake in the calf on post-therapy scan potentiates the role of somatostatin receptor scintigraphy in identifying macrophage-specific inflammatory reactions.
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Piyush Aggarwal, Kunal Ramesh Chandekar, Ashwani Sood, Shakti Zerial, Rajender Kumar, and Anindita Sinha declare that they have no conflict of interest.
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This study was performed in accordance with the ethical standards as laid down in the 2013 Declaration of Helsinki and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.
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Informed consent was obtained from the participant for the study mentioned as a part of the institutional protocol.
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Aggarwal, P., Chandekar, K.R., Sood, A. et al. Incidental Muscle Uptake of 177Lu-DOTATATE in Peripheral Vascular Disease. Nucl Med Mol Imaging 55, 320–322 (2021). https://doi.org/10.1007/s13139-021-00724-4
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DOI: https://doi.org/10.1007/s13139-021-00724-4