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Open-Mouth Bone Scintigraphy Is Better than Closed-Mouth Bone Scintigraphy in the Diagnosis of Temporomandibular Osteoarthritis

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Abstract

Purpose

Closed-mouth bone scintigraphy (CM scan) and closed-mouth single-photon emission computed tomography (CM SPECT) are used for conventional evaluation of osteoarthritis of the temporomandibular joint (TMJ). However, the adequacy of open-mouth bone scintigraphy (OM scan) has not yet been evaluated. Therefore, the purpose of this study was to compare the diagnostic performance of CM scan, CM SPECT, and OM scan.

Methods

Thirty-six patients with suspicion of an abnormality of the TMJ and who underwent a 99mTc-HDP CM scan, CM SPECT, and an OM scan were enrolled. The scans were assessed visually for the presence of positive focal uptake in the TMJ. Osteoarthritis was defined as arthralgia plus crepitus or radiologic signs of arthrosis.

Results

Of 72 TMJs, 21 (29.2 %) were diagnosed with osteoarthritis. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 90.5 %, 49.0 %, 42.2 %, 92.6 % and 61.1 % for the CM scan, 81.0 %, 58.8 %, 44.7 %, 88.2 % and 65.3 % for CM SPECT, and 81.0 %, 82.4 %, 65.4 %, 91.3 % and 81.9 % for the OM scan, respectively. The accuracy of the OM scan was higher than that of CM SPECT and the CM scans (p = 0.004 and p < 0.001, respectively).

Conclusions

The OM scan was more accurate than the conventional CM scan and even CM SPECT for diagnosing TMJ osteoarthritis.

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Acknowledgments

This work was supported by the Nuclear Safety Research Program through the Korea Foundation of Nuclear Safety (KOFONS) and the Nuclear Safety and Security Commission (NSSC), Republic of Korea (grant no. 1305033).

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Authors and Affiliations

  1. Department of Nuclear Medicine, Chonnam National University Hospital, 42 Jebong-ro, Donggu, Gwangju, 61469, Korea

    Ki Seong Park, Ho-Chun Song, Sang-Geon Cho, Sae-Ryung Kang, Jahae Kim & Haeng Man Jun

  2. Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun-gun, Korea

    Minchul Song, Geum-Cheol Jeong, Hee Jeong Park, Seong Young Kwon, Jung-Joon Min & Henry Hee-Seung Bom

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  1. Ki Seong Park
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Corresponding author

Correspondence to Ho-Chun Song.

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Conflicts of interest

Ki Seong Park, Ho-Chun Song, Sang-Geon Cho, Sae-Ryung Kang, Jahae Kim, Haeng Man Jun, Minchul Song, Geum-Cheol Jeong, Hee Jeong Park, Seong Young Kwon, Jung-Joon Min and Henry Hee-Seung Bom declare that they have no conflicts of interest.

Ethical statement

The study was approved by an institutional review board and was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The institutional review board waived the need for informed consent.

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Park, K.S., Song, HC., Cho, SG. et al. Open-Mouth Bone Scintigraphy Is Better than Closed-Mouth Bone Scintigraphy in the Diagnosis of Temporomandibular Osteoarthritis. Nucl Med Mol Imaging 50, 213–218 (2016). https://doi.org/10.1007/s13139-016-0407-z

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  • DOI: https://doi.org/10.1007/s13139-016-0407-z

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