Abstract
Metastases to orbit occur rarely but are the most common form of malignant orbital tumors. Usually the orbital metastases occur in disseminated disease. Very rarely orbital metastases can be the presenting feature of systemic malignancy. We report here a case with orbital metastases as the presenting feature of lung malignancy and describe the utility of FDG PET/CT as one-stop-shop imaging modality in this setting.
References
Shields JA, Shields CL, Brotman HK, Carvalho C, Perez N, Eagle Jr RC, et al. Cancer metastatic to the orbit: the 2000 Robert M. Curts Lecture. Ophthal Plast Reconstr Surg. 2001;17:346–54.
Ahmad SM, Esmaeli B. Metastatic tumors of the orbit and ocular adnexa. Curr Opin Ophthalmol. 2007;18:405–13.
Zografos L, Ducrey N, Beati D, Schalenbourg A, Spahn B, Balmer A, et al. Metastatic melanoma in the eye and orbit. Ophthalmology. 2003;110:2245–56.
Dieing A, Schulz CO, Schmid P, Roever AC, Lehenbauer-Dehm S, Jehn C, et al. Orbital metastases in breast cancer: report of two cases and review of the literature. J Cancer Res Clin Oncol. 2004;130:745–48.
Macedo JE, Machado M, Araujo A, Angélico V, Lopes JM. Orbital metastasis as a rare form of clinical presentation of nonsmall cell lung cancer. J Thorac Oncol. 2007;2:166–67.
Mehta JS, Abou-Rayyah Y, Rose GE. Orbital carcinoid metastases. Ophthalmology. 2006;113:466–72.
Deron PB, Bonte KM, Vermeersch HF, Van de Wiele C. Lymph node metastasis of squamous cell carcinoma from an unknown primary in the upper and middle neck: impact of (18) F-fluorodeoxyglucose positron emission tomography/computed tomography. Cancer Biother Radiopharm. 2011;26:331–4.
Moller AK, Loft A, Berthelsen AK. Damgaard Pedersen K, Graff J, Christensen CB et al. 18 F-FDG PET/CT as a diagnostic tool in patients with extracervical carcinoma of unknown primary site: a literature review. Oncologist. 2011;16:445–51.
Manohar K, Mittal BR, Kulkarni P, Singh N, Bhattacharya A, Gupta A. Usefulness of F-18 FDG PET/CT as one stop shop imaging modality for diagnosis of occult primary and estimation of disease burden in patients with intra-ocular masses. Clin Nucl Med [In press].
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Manohar, K., Mittal, B.R., Bhattacharya, A. et al. Orbital Metastases as Presenting Sign of Lung Carcinoma: Detection of Primary Malignancy and Disease Burden by F-18 FDG PET/CT. Nucl Med Mol Imaging 46, 73–75 (2012). https://doi.org/10.1007/s13139-011-0123-7
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DOI: https://doi.org/10.1007/s13139-011-0123-7