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Plant-Mediated Green Synthesis of Zinc Oxide Nanoparticles Using Swertia chirayita Leaf Extract, Characterization and Its Antibacterial Efficacy Against Some Common Pathogenic Bacteria

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Abstract

The use of plant materials for the green synthesis of zinc oxide nanoparticles has enormous applications in pharmaceuticals, biotechnological, and biological fields. In this paper, we report Swertia chirayita leaf extract-mediated green synthesis of zinc oxide nanoparticles (ZnONPs). Furthermore, the as-prepared ZnONPs were characterized by employing Fourier transform infrared spectroscopy (FTIR), x-ray diffraction (XRD), UV-visible spectroscopy (UV-VIS), high-resolution transmission electron microscopy (HR-TEM), scanning electron microscopy (SEM), and energy-dispersive x-ray spectroscopy (EDS). The antibacterial efficacy of green synthesized ZnONPs was investigated against Gram-positive (Staphylococcus aureus) as well as Gram-negative (Escherichia coli and Salmonella enterica) bacterial strains. The efficacy of Swertia chirayita-extracted ZnONPs were found to be effective against Gram-positive as well as Gram-negative bacterial strains, suggesting its plausible use in cases of resistant bacterial infections.

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References

  1. Akhter, S. M. H., Mohammad, F., & Ahmad, S. (2016). Plant mediated green synthesis of metal nanoparticles for applications in medicine. Journal of Nanotechnology in Diagnosis and Treatment, 4, 15–24.

    Article  Google Scholar 

  2. Hiremath, S., Vidya, C., Antonyraj, M. A. L., Chandraprabha, M. N., & Gandhi, P. (2013). Biosynthesis of Zn nanoparticles assisted by Euphorbia tirucalli (pencil cactus). Int. J. Curr. Eng. Technol, 1, 176–179.

    Google Scholar 

  3. Abboud, Y., Saffaj, T., Chagraoui, A., El Bouari, A., Brouzi, K., Tanane, O., & Ihssane, B. (2014). Biosynthesis, characterization and antimicrobial activity of copper oxide nanoparticles (CONPs) produced using brown alga extract (Bifurcaria bifurcata). Applied Nanoscience, 4, 571–576.

    Article  Google Scholar 

  4. Prashant, M., Rana, N. K., & Yadav, S. K. (2008). Biosynthesis of nanoparticles: technological concepts and future applications. Journal of Nanoparticle Research, 10, 507–517.

    Article  Google Scholar 

  5. Salam, H. A., Sivaraj, R., & Venckatesh, R. (2014). Green synthesis and characterization of zinc oxide nanoparticles from Ocimum basilicum L. var. purpurascens Benth.-Lamiaceae leaf extract. Materials Letters, 131, 16–18.

    Article  Google Scholar 

  6. Wang, X., Lu, J., Xu, M., & Xing, B. (2008). Sorption of pyrene by regular and nanoscaled metal oxide particles: influence of adsorbed organic matter. Environmental Science & Technology, 42, 7267–7272.

    Article  Google Scholar 

  7. Hsu, C. Y., Ko, T. F., & Huang, Y. M. (2008). Influence of ZnO buffer layer on AZO film properties by radio frequency magnetron sputtering. Journal of the European Ceramic Society, 28, 3065–3070.

    Article  Google Scholar 

  8. Yousef, M. J., & Danial, E. N. (2012). In vitro antibacterial activity and minimum inhibitory concentration of zinc oxide and nano-particle zinc oxide against pathogenic strains. Journal of Health Sciences, 2, 38–42.

    Google Scholar 

  9. Sangeetha, G., Rajeshwari, S., & Venckatesh, R. (2011). Green synthesis of zinc oxide nanoparticles by aloe barbadensis miller leaf extract: structure and optical properties. Materials Research Bulletin, 46(12), 2560–2566.

    Article  Google Scholar 

  10. Xiao, J., Muxia, W., Kai, G., Wang, F., Cao, H., & X, Y. (2011). ZnO-ZnS QDs interfacial heterostructure for drug and food delivery application: enhancement of the binding affinities of flavonoid aglycones to bovine serum albumin. Nanomedicine: Nanotechnology, Biology and Medicine., 7, 850–858.

    Article  Google Scholar 

  11. Ravichandran, K., Karthika, K., Sakthivel, B., Begum, N. J., Snega, S., Swaminathan, K., & Senthamilselvi, V. (2014). Tuning the combined magnetic and antibacterial properties of ZnO nanopowders through Mn doping for biomedical applications. Journal of Magnetism and Magnetic Materials, 358, 50–55.

    Article  Google Scholar 

  12. Ahmed, S., Chaudhry, S. A., & Ikram, S. (2017). A review on biogenic synthesis of ZnO nanoparticles using plant extracts and microbes: a prospect towards green chemistry. Journal of Photochemistry and Photobiology B: Biology, 166, 272–284.

    Article  Google Scholar 

  13. Kumar, V., & Staden, J. V. (2016). A review of Swertia chirayita (Gentianaceae) as a traditional medicinal plant. Frontiers in Pharmacology, 6, 308.

    Article  Google Scholar 

  14. Akhter, S. M. H., Mahmood, Z., Mohammad, F., & Ahmad, S. (2017). Ultra-small copper oxide nanoparticles (ucuonps ): Swertia chirayita mediated facile green synthesis, physicochemical, characterization and antibacterial efficacy. International Journal of Current Engineering and Scientific research, 4, 11–20.

    Google Scholar 

  15. Chaudhuri, S. K., & Malodia, L. (2017). Biosynthesis of zinc oxide nanoparticles using leaf extract of Calotropis gigantea: characterization and its evaluation on tree seedling growth in nursery stage. Applied Nanoscience, 7, 501–512.

    Article  Google Scholar 

  16. Dobrucka, R., & Długaszewska, J. (2016). Biosynthesis and antibacterial activity of ZnO nanoparticles using Trifolium pratense flower extract. Saudi Journal of Biological Sciences, 23(4), 517–523.

    Article  Google Scholar 

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Acknowledgements

The author acknowledges USIF of AMU for TEM and SEM.

Funding

This work received support from UGC in the form of Maulana Azad National Fellowship for Minority Students.

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Authors and Affiliations

  1. Department of Applied Chemistry, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh, India

    Syed Md Humayun Akhter & Faiz Mohammad

  2. Department of Microbiology, The Himalaya Drug Company, Dehradun, India

    Zafar Mahmood

  3. Institute of Ophthalmology, Faculty of Medicine, Aligarh Muslim University, Aligarh, India

    Shamim Ahmad

Authors
  1. Syed Md Humayun Akhter
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  2. Zafar Mahmood
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  3. Shamim Ahmad
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  4. Faiz Mohammad
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Correspondence to Faiz Mohammad.

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Akhter, S.M.H., Mahmood, Z., Ahmad, S. et al. Plant-Mediated Green Synthesis of Zinc Oxide Nanoparticles Using Swertia chirayita Leaf Extract, Characterization and Its Antibacterial Efficacy Against Some Common Pathogenic Bacteria. BioNanoSci. 8, 811–817 (2018). https://doi.org/10.1007/s12668-018-0549-9

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