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Esophageal basaloid squamous cell carcinoma presenting as a subepithelial lesion

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Abstract

Basaloid squamous cell carcinoma of the esophagus is rare and generally detected at advanced stage, and its prognosis is poorer than that of conventional esophageal squamous cell carcinoma. Therefore, detection at the early stage is crucial for patient survival. We experienced an elevated esophageal basaloid squamous cell carcinoma presenting as a subepithelial tumor-like lesion. Although the lesion needed to be differentiated from subepithelial tumor, we diagnosed it as early stage and treated with endoscopic submucosal dissection. We report the macroscopic and microscopic findings of basaloid carcinoma through this case along with a review of the relevant literature.

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References

  1. Chen SB, Weng HR, Wang G, et al. Basaloid squamous cell carcinoma of the esophagus. J Cancer Res Clin Oncol. 2012;138:1165–71.

    Article  Google Scholar 

  2. Takemura M, Yoshida K, Fujiwara Y, et al. A case of long-term survival after pulmonary resection for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the esophagus. Int J Surg Case Rep. 2012;3:451–4.

    Article  Google Scholar 

  3. Liu L, Xue X, Xue L. Liver metastatic basaloid squamous cell carcinoma with negative expression of pancytokeratin: a case report and literature review. Diagn Pathol. 2019;14:102.

    Article  Google Scholar 

  4. Yamasaki T, Ishii N, Okuno T, et al. A case of esophageal squamous cell carcinoma with neuroendocrine, basaloid, and ciliated glandular differentiation. Clin J Gastroenterol. 2021;14:32–8.

    Article  Google Scholar 

  5. Kobayashi Y, Nakanishi Y, Taniguchi H, et al. Histological diversity in basaloid squamous cell carcinoma of the esophagus. Dis Esophagus. 2009;22:231–8.

    Article  CAS  Google Scholar 

  6. Tada T, Honma R, Imai JI, et al. A novel gene expression scoring system for accurate diagnosis of basaloid squamous cell carcinoma of the esophagus. Int J Oncol. 2017;51:877–86.

    Article  CAS  Google Scholar 

  7. Di L, Fu KI, Wu X, et al. Endoscopic features and associated histology of an basaloid squamous cell carcinoma of the esophagus at the very early stage. BMC Cancer. 2019;19:513.

    Article  Google Scholar 

  8. Kim SB, Lee SH, Jeong DE, et al. Esophageal basaloid squamous carcinoma treated by endoscopic resection and radiation. Korean J Gastroenterol. 2018;72:258–61.

    Article  Google Scholar 

  9. Kai Y, Kato M, Hayashi Y, et al. Esophageal early basaloid squamous carcinoma with unusual narrowband imaging magnified endoscopy findings. World J Gastroenterol. 2014;20:12673–7.

    Article  Google Scholar 

  10. Nakamura M, Nishikawa J, Suenaga S, et al. A case of EMRC for basaloid squamous carcinoma of the cervical esophagus. World J Gastrointest Endosc. 2012;4:373–5.

    Article  Google Scholar 

  11. Oyama T, Inoue H, Arima M, et al. Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology: magnifying endoscopic classification of the Japan Esophageal Society. Esophagus. 2017;14:105–12.

    Article  Google Scholar 

  12. Salami A, Abbas AE, Petrov R, et al. Comparative analysis of clinical, treatment, and survival characteristics of basaloid and squamous cell carcinoma of the esophagus. J Am Coll Surg. 2018;226:1086–92.

    Article  Google Scholar 

  13. Nosaka T, Suto H, Matsuda H, et al. A case of superficial esophageal basaloid squamous cell carcinoma resected by endoscopic submucosal dissection. Nihon Shokakibyo Gakkai Zasshi. 2014;111:1105–12.

    PubMed  Google Scholar 

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Acknowledgements

Endoscopic members in St. Luke’s International hospital.

Funding

This study was not supported by any funding.

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Contributions

YS and KT performed the endoscopy. YS, KT, and KF managed the patient. NK evaluated the pathology of esophageal cancer specimen. YS drafted the manuscript. YS, NK, KK, and KF edited and revised the manuscript.

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Correspondence to Yasutoshi Shiratori.

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Informed consent was obtained from the patient.

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Shiratori, Y., Kanomata, N., Takagi, K. et al. Esophageal basaloid squamous cell carcinoma presenting as a subepithelial lesion. Clin J Gastroenterol 14, 1324–1328 (2021). https://doi.org/10.1007/s12328-021-01449-9

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  • DOI: https://doi.org/10.1007/s12328-021-01449-9

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