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Recurrence of primary squamous cell carcinoma of the ileum diagnosed by elevation of serum SCC: report of a case

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Abstract

Primary squamous cell carcinoma of the intestine is extremely rare. This report describes a patient with primary squamous cell carcinoma of the small intestine. A 72-year-old Japanese woman was referred to our hospital because of a diagnosis of intestinal obstruction. She underwent laparotomy owing to the diagnosis of mechanical intestinal obstruction due to a pelvic mass after conservative treatment. The affected ileum was resected, and histopathological examination revealed proliferation of differentiated squamous cell carcinoma at the submucosal area with no adenocarcinoma component. At the 4th month after the operation, the level of serum squamous cell carcinoma (SCC) antigen was elevated. At 6 months after the operation, the serum SCC value was further elevated, and enhanced CT revealed two new pelvic tumors with enhancement at the mesentery and free space. A second laparotomy was performed 8 months after the operation. Histopathological examination showed differentiated squamous cell carcinoma as in the first operation. The level of serum SCC decreased at the 28th postoperative day. Chemotherapy including carboplatin and paclitaxel was performed as an adjuvant regimen. The patient has experienced no recurrence of squamous cell carcinoma for 55 months.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of First Surgery, Hokkaido University Graduate School of Medicine, Kita-ku, Kita 15, Nishi 7, Sapporo, Hokkaido, 060-8638, Japan

    Kazuhiro Mino & Satoru Todo

  2. Kawanishi Surgical Hospital, Sapporo, Hokkaido, Japan

    Naoki Kamii & Norio Kawanishi

  3. Department of Pediatric Surgery, Hokkaido University Hospital, Sapporo, Hokkaido, Japan

    Tadao Okada

Authors
  1. Kazuhiro Mino
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  2. Naoki Kamii
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  3. Norio Kawanishi
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  4. Tadao Okada
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  5. Satoru Todo
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Corresponding author

Correspondence to Kazuhiro Mino.

Additional information

This article is based on a study first reported in the Hokkaido Journal of Surgery. [Mino K, Kamii N, Hashimoto S, Yamada S, Kawanishi N. A case of primary squamous cell carcinoma of ileum. Hokkaido J Surg. 2010;55(1):33–8.]

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Mino, K., Kamii, N., Kawanishi, N. et al. Recurrence of primary squamous cell carcinoma of the ileum diagnosed by elevation of serum SCC: report of a case. Clin J Gastroenterol 5, 239–244 (2012). https://doi.org/10.1007/s12328-012-0309-2

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  • DOI: https://doi.org/10.1007/s12328-012-0309-2

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