Abstract
Rh blood group system is a complex blood group system. Rh antibodies are produced in Rh negative individuals following exposure to foreign RBCs after transfusion or pregnancy. Anti C is a rare cause of hemolytic disease of newborn and is very scarcely reported in the literature. The aim of the present case report of Hemolytic disease caused by Anti C antibody is to bring out the fact that antibodies other than anti D should be considered in cases that give a suggestive history but no evidence of Anti D.
References
Harmening DM (ed) (2005) Modern blood banking and transfusion practices, 5th edn. F A Davis Company, Philadelphia
Baker JW, Harrison KL, Harvey PJ (1981) Anti-C haemolytic disease requiring intrauterine and exchange transfusion. Med J Aust 2(6):296
Trevett TN Jr, Moise KJ Jr (2005) Twin pregnancy complicated by severe hemolytic disease of the fetus and newborn due to anti-g and anti-C. Obstet Gynecol 106(5 Pt 2):1178–1180
Mitchell S, James A (1999) Severe hemolytic disease from rhesus anti-C antibodies in a surrogate pregnancy after oocyte donation: a case report. J Reprod Med. 44(4):388–390
Moise KJ Jr (2000) Non-anti-D antibodies in red-cell alloimmunization. Eur J Obstet Gynecol Reprod Biol 92(1):75–81
Koelewijn JM, Vrijkotte TG, van der Schoot CE, Bonsel GJ, de Haas M (2008) Effect of screening for red cell antibodies, other than anti-D, to detect hemolytic disease of the fetus and newborn: a population study in the Netherlands. Transfusion 48(5):941–952
Chu HP, Kanagalingam D, Chan DK (2007) Severe intrauterine hemolysis due to anti-C(w). Am J Perinatol 24(10):623–626 (Epub 30 Oct 2007)
May-Wewers J, Kaiser JR, Moore EK, Blackall DP (2006) Severe neonatal hemolysis due to a maternal antibody to the low-frequency Rh antigen C (w). Am J Perinatol 23(4):213–217 (Epub 4 Apr 2006)
Kollamparambil TG, Jani BR, Aldouri M, Soe A, Ducker DA (2005) Anti-C(w) alloimmunization presenting as hydrops fetalis. Acta Paediatr 94(4):499–501
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Negi, G., Singh, G.D. Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?. Indian J Hematol Blood Transfus 28, 121–122 (2012). https://doi.org/10.1007/s12288-011-0105-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12288-011-0105-z