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The Efficacy and Safety of Systemic Antifungals in Children’s Onychomycosis

  • Fungal Infections of Skin and Subcutaneous Tissue (A Bonifaz, Section Editor)
  • Published:
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Abstract

Purpose of Review

There are few reports about onychomycosis in children with inconclusive results about the better and safer option. We have observed and reported on the literature a significant increase in the prevalence of onychomycosis in this age group.

Recent Findings

Fungal infections, especially on the nails, are common health diseases with increasing prevalence according to age; however, it is rare in the pediatric population, except in patients with Down syndrome and primary and secondary immunodeficiency.

Summary

In this review, we focused on characteristics of children’s onychomycosis as well as the efficacy and safety of systemic antifungals, mainly terbinafine and itraconazole. Clinicians must consider onychomycosis as the differential diagnosis of nail disease in children and be aware of the adverse events of systemic treatments in onychomycosis.

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Authors and Affiliations

  1. Dermatology Department, Hospital General de México, Dr. Balmis 148, Col. Doctores, Deleg. Cuauhtémoc, C.P. 06726, México D.F, Mexico

    Andrés Tirado-Sánchez & Alexandro Bonifaz

  2. Dermatology Department, Instituto Mexicano del Seguro Social, Ciudad de México, Mexico

    Andrés Tirado-Sánchez

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  1. Andrés Tirado-Sánchez
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  2. Alexandro Bonifaz
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Correspondence to Andrés Tirado-Sánchez.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Fungal Infections of Skin and Subcutaneous Tissue

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Tirado-Sánchez, A., Bonifaz, A. The Efficacy and Safety of Systemic Antifungals in Children’s Onychomycosis. Curr Fungal Infect Rep 11, 104–109 (2017). https://doi.org/10.1007/s12281-017-0280-y

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