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How to Enhance the Accuracy of the Allen’s Test with Indocyanine Green Fluorescence Video-Angiography

  • Surgical Techniques and Innovations
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Abstract

Introduction

Free flaps are routinely used in head and neck surgery for reconstruction after major ablative procedures. Among these, radial forearm free flap (RFFF) still represents a workhorse. Regarding its harvesting, donor site complications are described, with acute hand ischemia as the most feared one. To evaluate residual hand perfusion through the ulnar axis, several methods are commonly used in clinical practice, such as the modified Allen’s test (MAT) and Doppler ultrasound. Nevertheless, contradictory results are not uncommon. Indocyanine green (ICG) fluorescence video-angiography (ICG-VA) is a technique recently introduced in flap surgery to evaluate tissue perfusion, which may be employed during RFFF harvesting to enhance the accuracy of the traditional tests.

Patients and Methods

To assess the dual blood supply in the donor site prior to harvesting a RFFF, we performed MAT, Doppler ultrasound, and ICG-VA in a patient suffering from oropharyngeal cancer who underwent major ablative and reconstructive surgery. The technique is described in the Video.

Results

Clinical MAT was judged as “positive,” highlighting an adequate dual blood supply to the hand, and the upper limb Doppler ultrasound showed a normal blood flow. Similarly, also ICG-VA pointed out a good hand perfusion pattern with a thenar-to-hypothenar ICG ratio of over 25%. Thus, we proceeded with RFFF harvesting without evidence of ischemic complications at the donor site in the postoperative course.

Conclusions

ICG-VA represents a safe and useful procedure to reduce donor site morbidity during RFFF harvesting, enhancing the sensitivity of the clinical MAT, and potentially detecting its (rare) false positive results.

Level of Evidence: Level V.

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References

  1. Surowitz JB, Most SP (2015) Use of laser-assisted indocyanine green angiography for early division of the forehead flap pedicle. JAMA Facial Plast Surg 17(3):209–214. https://doi.org/10.1001/jamafacial.2015.0171

    Article  PubMed  Google Scholar 

  2. Giordano L, Galli A, Familiari M et al (2022) Head and neck pedicled flap autonomization using a new high-resolution indocyanine green fluorescence video-angiography device. Head Neck 44(6):1496–1499. https://doi.org/10.1002/hed.27051

    Article  PubMed  PubMed Central  Google Scholar 

  3. Taylor SR, Jorgensen JB (2015) Use of fluorescent angiography to assess donor site perfusion prior to free tissue transfer. Laryngoscope 125(6):E192–E197. https://doi.org/10.1002/lary.25190

    Article  PubMed  Google Scholar 

  4. Yang GF, Chen PJ, Gao YZ et al (1997) Forearm free skin flap transplantation: a report of 56 cases. Br J Plast Surg 50(3):162–165. https://doi.org/10.1016/S0007-1226(97)91363-1

    Article  CAS  PubMed  Google Scholar 

  5. Bruner TW, Hanasono MM, Skoracki RJ (2011) Radial forearm free flap morbidity: a rare case of a normal preoperative arteriogram and acute intraoperative hand ischemia. Can J Plast Surg 19(3):102–104. https://doi.org/10.1177/229255031101900314

    Article  PubMed  PubMed Central  Google Scholar 

  6. Müller-Richter UD, Driemel O, Mörtl M et al (2008) The value of Allen’s test in harvesting a radial forearm flap: correlation of ex-vivo angiography and histopathological findings. Int J Oral Maxillofac Surg 37(7):672–674. https://doi.org/10.1016/j.ijom.2008.01.012

    Article  PubMed  Google Scholar 

  7. Jones BM, O’Brien CJ (1985) Acute ischaemia of the hand resulting from elevation of a radial forearm flap. Br J Plast Surg 38(3):396–397. https://doi.org/10.1016/0007-1226(85)90250-4

    Article  CAS  PubMed  Google Scholar 

  8. Wood JW, Broussard KC, Burkey B (2013) Preoperative testing for radial forearm free flaps to reduce donor site morbidity. JAMA Otolaryngol Head Neck Surg 139(2):183–186. https://doi.org/10.1001/jamaoto.2013.1357

    Article  PubMed  Google Scholar 

  9. Zisquit J, Velasquez J, Nedeff N (2022) Allen test. In: StatPearls. Treasure Island: StatPearls Publishing, Available from: https://www.ncbi.nlm.nih.gov/books/NBK507816/

  10. Barbeau GR, Arsenault F, Dugas L, Simard S, Larivière MM (2004) Evaluation of the ulnopalmar arterial arches with pulse oximetry and plethysmography: comparison with the Allen’s test in 1010 patients. Am Heart J 147(3):489–493. https://doi.org/10.1016/j.ahj.2003.10.038

    Article  PubMed  Google Scholar 

  11. Li K, Zhang Z, Nicoli F et al (2018) Application of indocyanine green in flap surgery: a systematic review. J Reconstr Microsurg 34(2):77–86. https://doi.org/10.1055/s-0037-1606536

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

Authors

Contributions

All authors contributed to the study’s conception and design. Material preparation, data collection, and analysis were performed by Leone Giordano, Andrea Galli, Marco Familiari, and Ayhan Irem. The first draft of the manuscript was written by Leone Giordano, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Andrea Galli.

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Ethics Approval

The study was conducted according to the ethical standards established in the 1964 Declaration of Helsinki and revised in 2008. The present protocol was approved by our Institutional Review Board (protocol number: 181/INT/2021; approval date: 15/12/2021).

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Informed consent was obtained from the patient included in the study.

Conflict of Interest

The authors declare no competing interests.

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Giordano, L., Familiari, M., Irem, A. et al. How to Enhance the Accuracy of the Allen’s Test with Indocyanine Green Fluorescence Video-Angiography. Indian J Surg 85, 1242–1244 (2023). https://doi.org/10.1007/s12262-023-03672-9

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  • DOI: https://doi.org/10.1007/s12262-023-03672-9

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