Abstract
Evaluation of platelet count and its significance in early detection of post burn septicemia for commencement of timely vigorous treatment against it. Studies investigating the role of platelets and platelet count in burn patients are rare, rather old and mostly presenting case reports. Septicemia is the most important cause of mortality in burns. Burn patients can only be saved if septicemia is detected early which requires very sensitive prognostic indicator. Total 594 adult burn patients were studied, by observing them for septicemia and studying their subsequent platelet counts using visual method. In non-survivors (256) gradual decline in platelet count was observed and minimal platelet count was observed before death of the patient, while in survivors (338) gradual rise in platelet count was observed. No significant variation observed in other laboratory parameters such as total neutrophil count and serum creatinine. In significant number of non survivor (62.11%) platelet count was low before their death and in significant number of survivor (86.09%) platelet count was normal before their discharge. Thus it is conclude that serial declining platelet count is a very sensitive prognostic factor in early detection of post burn septicemia.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Pavic M, Milevoj L (2007) Platelet count monitoring in burn patients. Biochemia Medica 17(2):212–219
Macedo JLS, Santos JB (2007) Predictive factors of mortality in burn patients. Rev Inst Med Trop 49(6):365–370
Vilain RC (1977) Is the burn center a septic ghetto? Plast Reconstr Surg 59(5):793–794
El-Sonbaty MA, El-Otiefy MA (1996) Haematological change in severely burn patients. Ann Burns Fire Disasters 9(4):1–4
Yoshiaki T (1997) Blood platelet in severely injured burned patients. Burns 23(78):593–595
Caprini JA, Lipp V, Zuckerman L et al (1977) Hematologic changes following burns. J Surg Res 22(6):626–635
Eurenius K, Mortensen RF, Meserol PM et al (1972) Platelet and megakaryocyte kinetics following thermal injury. J Lab Clin Med 79(2):247–257
Sarda DK, Dagwade AM, Lohiya S et al (2005) Evauation of platelet count as a prognostic indicator in early detection of post burn septicaemia. Bombay Hosp J 47(3):3–6
Cohen P, Gardner FH (1966) Thrombocytopenia as a laboratory sign and complication of gram negative bacteremic infection. Arch Intern Med 117:113–123
Maduli IC, Patil A, Pardhan NR et al (1999) Evaluation of burn sepsis with reference to platelet count as a prognostic indicator. IJS 61(4):235–238
Housinger TA, Brinkerhoff C, Warden GD (1993) The relationship between platelet count, sepsis and survival in pediatric burn patients. Arch Surg 128:65–67
Wang Y, Tang HT, Xia ZF et al (2010) Factor affecting survival in adult patient with massive burn. Burns 36(1):57–64
Mariano F, Cantaluppi V, Stella M (2008) Circulating plasma factors induce tubular and glomerular alterations in septic burns patients. Crit Care 12:42
Acknowledgement
Dr.B.S.Gedam, MBBS, MS.GEN.Surgery, M.S.ortho, Professor in surgery, is heartily thanked for his technical assistance in the preparation of the manuscript.
Funding/Support Source
None.
Author information
Authors and Affiliations
Corresponding author
Additional information
This original article is not presented or sent in any other journal for publication other than Indian journal of surgery.
Rights and permissions
About this article
Cite this article
Gajbhiye, A.S., Meshram, M.M. & Kathod, A.P. Platelet Count as a Prognostic Indicator in Burn Septicemia. Indian J Surg 75, 444–448 (2013). https://doi.org/10.1007/s12262-012-0532-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-012-0532-6