Abstract
Eosinophilia can be a manifestation of a variety of causes such as infections, allergic reactions and autoimmune processes. Also, it is described in various solid malignancies in the presence of tumour eosinophilic infiltration. We report a patient of high-grade urinary bladder cancer with eosinophilic leukemoid reaction and tumour histopathology demonstrated diffuse infiltration of eosinophils. Though the entity is described to carry a good prognosis in literature, our experience is totally different as the patient deteriorated rapidly in a matter of days, was deemed inoperable in view of worsening performance status and was referred for palliative management.
References
Lowe D, Jorizzo J, Hutt MS (1981 Dec) Tumour-associated eosinophilia: a review. J Clin Pathol 34(12):1343–1348
Flamm J (1992 Aug) Tumor-associated tissue inflammatory reaction and eosinophilia in primary superficial bladder cancer. Urology. 40(2):180–185
Lowe D, Fletcher CD, Gower RL (1984 May) Tumour-associated eosinophilia in the bladder. J Clin Pathol 37(5):500–502
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Harsha, B.S., Manikandan, R., Sreerag, K.S. et al. Eosinophilic Leukemoid Reaction with Eosinophilic Tumor Tissue Infiltration as an Extermely Poor Prognostic Factor in Urinary Bladder Cancer- a Known Entity Revisited. Pathol. Oncol. Res. 26, 2817–2819 (2020). https://doi.org/10.1007/s12253-020-00807-1
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DOI: https://doi.org/10.1007/s12253-020-00807-1