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Eosinophilic Leukemoid Reaction with Eosinophilic Tumor Tissue Infiltration as an Extermely Poor Prognostic Factor in Urinary Bladder Cancer- a Known Entity Revisited

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Pathology & Oncology Research

Abstract

Eosinophilia can be a manifestation of a variety of causes such as infections, allergic reactions and autoimmune processes. Also, it is described in various solid malignancies in the presence of tumour eosinophilic infiltration. We report a patient of high-grade urinary bladder cancer with eosinophilic leukemoid reaction and tumour histopathology demonstrated diffuse infiltration of eosinophils. Though the entity is described to carry a good prognosis in literature, our experience is totally different as the patient deteriorated rapidly in a matter of days, was deemed inoperable in view of worsening performance status and was referred for palliative management.

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Authors and Affiliations

  1. Department of Urology and Renal Transplantation, JIPMER, Puducherry, India

    Bokka Sri Harsha, R. Manikandan, K. S. Sreerag & L. N. Dorairajan

  2. Department of Pathology, JIPMER, Puducherry, India

    N. G. Rajesh & Rakhi Kar

Authors
  1. Bokka Sri Harsha
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  2. R. Manikandan
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  3. K. S. Sreerag
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  4. L. N. Dorairajan
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  5. N. G. Rajesh
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  6. Rakhi Kar
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Correspondence to Bokka Sri Harsha.

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Harsha, B.S., Manikandan, R., Sreerag, K.S. et al. Eosinophilic Leukemoid Reaction with Eosinophilic Tumor Tissue Infiltration as an Extermely Poor Prognostic Factor in Urinary Bladder Cancer- a Known Entity Revisited. Pathol. Oncol. Res. 26, 2817–2819 (2020). https://doi.org/10.1007/s12253-020-00807-1

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  • DOI: https://doi.org/10.1007/s12253-020-00807-1

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