Skip to main content

Advertisement

Log in

Two cases of severe invasive infections in children caused by Streptococcus pneumoniae serotype 14 — case report

  • Published:
Folia Microbiologica Aims and scope Submit manuscript

Abstract

Two cases are presented of severe pneumococcal infections in infants caused by serotype 14 Streptococcus pneumoniae. The first case — meningitis — caused by S. pneumoniae (pneumococcus) with lowlevel penicillin susceptibility has developed from acute otitis media and resulted in fatal outcome. The second one — an immunocompromised child presenting recurrent otitis and chronic mastoiditis developed into pneumococcal pneumonia. Both cases demonstrate the extreme importance of a relevant initial treatment of localized pneumococcal infections, preventing the development of generalized infection. Amoxicillin (an oral treatment option in both upper and lower respiratory tract infections caused also by Pneumococcus strains with low-level penicillin susceptibility due to its beneficial pharmacokinetics and pharmacodynamics) was not used in either case.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Abbreviations

AOM:

acute otitis media

CT:

computer tomograph (scan)

CNS:

central nervous system

IZ:

inhibitory zone

References

  • Aguilar A., Robledo O., Gimenez M.J., Tarrago D., Grazino J.J., Gimeno M., Coronel P.: Influence of the β-lactam-resistance phenotype on the cefuroxime versus cefditoren susceptibility of Streptococcus penumoniae and Haemophilus influenzae recovered from children with acute otitis media. J.Antimicrob.Chemother.60, 323–327 (2007).

    Article  PubMed  Google Scholar 

  • AAP (American Academy of Pediatrics and American Academy of Family Physicians): Diagnosis and management of acute otitis media. Pediatrics113, 1451–1465 (2004).

    Article  Google Scholar 

  • Bébrová E., Jindrák V., Kolář M., Marešová V., Urbášková P.: The schedule recommended for antibiotic treatment of respiratory diseases in primary medical care. (In Czech) Praktický lékař83, 502–515 (2003).

    Google Scholar 

  • Breuggemann A.B., Griffiths D.T., Meats E., Peto T., Crook D.W., Spratt B.G.: Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potential. J.Infect.Dis.187, 1421–1432 (2003).

    Google Scholar 

  • Butler C.C., Hood K., Verheij T., Little P., Melbye H., Nuttall J., Kelly M.J., Molstad S., Godycki-Cwirko M., Almirall J., Torres A., Gillespie D., Rautakorpi U., Coenen S., Goossens H.: Variation in antibiotic prescribing and its impact on recovery in patients with acute cough in primary care: prospective study in 13 countries. Brit.Med.J.338, b2242 (2009); bmj.com.

    Article  CAS  PubMed  Google Scholar 

  • Corbeel L.: Pneumococcal meningitis and otitis media. Eur.J.Pediatr.165, 283–284 (2006).

    Article  CAS  PubMed  Google Scholar 

  • Figueiredo A.M., Austrian R., Urbášková P., Teixeira L.A., Tomasz A.: Novel penicillin-resistant clones of Streptococcus pneumoniae in the Czech Republic and in Slovakia. Microb.Drug Resist.1, 71–78 (1995).

    Article  CAS  PubMed  Google Scholar 

  • Moravčík P., Čechová A., Galanda V., Marčeková D., Zavarská Ľ.: Isolation of multiresistant pneumococci from clinical material. (In Slovak) Bratisl.Lek.Listy80, 176–184 (1983).

    PubMed  Google Scholar 

  • Reichler M.R., Rakovsky J., Sobotova A., Slaciková M., Hlavacová B., Hill B., Krajciková L., Tarina P., Facklam R.R., Breiman R.F.: Multiple antimicrobial resistance of pneumococci in children with otitis media, bacteremia and meningitis in Slovakia. J.Infect.Dis.171, 1491–1496 (1995).

    CAS  PubMed  Google Scholar 

  • Reichler M.R., Rakovsky J., Slacikova M., Hlavacova B., Krajcikova L., Tarina P., Sobotova A., Facklam R.R., Breiman R.F.: Spread of multidrug-resistant Streptococcus pneumoniae among hospitalized children in Slovakia. J.Infect.Dis.173, 374–379 (1996).

    CAS  PubMed  Google Scholar 

  • Slobodníková L., Kotulová D., Kapellerová A., Kotzigová A.: Susceptibility of Streptococcus pneumoniae isolated from the respiratory tract of hospitalized children with respiratory tract infections. Bratisl.Lek.Listy11, 587–592 (1999).

    Google Scholar 

  • Spiro D.M., Tay K.Y., Arnold D.H., Dziura J.D., Baker M.D., Shapiro E.D.: Wait-and-see prescription for the treatment of acute otitis media. JAMA296, 1235–1241 (2006).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Hupková.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hupková, H., Urbančíková, I., Bazárová, K. et al. Two cases of severe invasive infections in children caused by Streptococcus pneumoniae serotype 14 — case report . Folia Microbiol 54, 563–565 (2009). https://doi.org/10.1007/s12223-009-0083-9

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12223-009-0083-9

Keywords

Navigation