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Recent Advances in Electrochemical Oxidation to Construct C–O Bonds

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Abstract

C–O bonds are widely found in pharmaceuticals and natural products and have various pharmacological activities. Therefore, developing effective strategies for constructing compounds containing C–O bonds has become a research hotspot among chemists. Organic electrochemical synthesis is a green, mild, and efficient strategy that shows great potential in the synthesis of compounds containing C–O bonds. This review introduces the reactions of compounds containing C–O bonds recently constructed by electrochemical methods and expounds the corresponding reaction mechanism to provide a reference for applying such reactions in organic synthesis.

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Acknowledgments

This work was supported by the Open Project Program of Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, Guilin Medical University (2022-GKLEH-08).

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Authors and Affiliations

  1. Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin, 541004, China

    Lei Zhan, Wan-Jie Wei, Cai-Nai Jiang, Lei Gao & Xian-Li Ma

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Zhan, L., Wei, WJ., Jiang, CN. et al. Recent Advances in Electrochemical Oxidation to Construct C–O Bonds. Trans. Tianjin Univ. 28, 482–505 (2022). https://doi.org/10.1007/s12209-022-00345-8

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