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Influence of respiration on dose calculation in stereotactic body radiotherapy of the lung

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Abstract

Our purpose in this study was to evaluate the variation in calculated doses caused by respiration in stereotactic body radiotherapy (SBRT) of the lung. The study targeted ten patients who underwent SBRT for lung tumors. CT images were acquired during free breathing and in the inhalation and exhalation phases. We compared the CT image at inhalation with the image at exhalation so as to measure the change in lung volume, variation in the CT value, and displacement of the chest wall. The lung volume change was shown to be correlated with the maximum of the chest wall motion and with the variation in the CT value. A statistically significant difference was observed in the CT values between inhalation and exhalation (p < 0.05). The total dose variation at the isocenter was confined within ±2 %. However, the dose from individual beams can vary significantly when the chest wall moves more than 10 mm in natural breathing.

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Conflict of interest

No actual or potential conflicts of interest exist for all authors.

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Authors and Affiliations

  1. Graduate School of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sapporo, 060-0812, Japan

    Rie Yamazaki

  2. Department of Radiation Medicine, Hokkaido University School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan

    Rikiya Onimaru, Norio Katoh, Tetsuya Inoue & Hiroki Shirato

  3. Faculty of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sapporo, 060-0812, Japan

    Takeshi Nishioka & Hiroyuki Date

Authors
  1. Rie Yamazaki
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  2. Rikiya Onimaru
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  3. Norio Katoh
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  4. Tetsuya Inoue
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  5. Takeshi Nishioka
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  6. Hiroki Shirato
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  7. Hiroyuki Date
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Corresponding author

Correspondence to Hiroyuki Date.

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Yamazaki, R., Onimaru, R., Katoh, N. et al. Influence of respiration on dose calculation in stereotactic body radiotherapy of the lung. Radiol Phys Technol 7, 284–289 (2014). https://doi.org/10.1007/s12194-014-0263-4

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  • DOI: https://doi.org/10.1007/s12194-014-0263-4

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