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Calibration of complex mixtures in one sweep

  • Original Research
  • Published:
International Journal for Ion Mobility Spectrometry

Abstract

The calibration of extremely complex humid gas-phase mixtures – often required in ion mobility spectrometry applications – is challenging, even when high-performance calibration gas generators such as HovaCAL® are applied. Here, we describe an approach to develop and apply mixtures of VOCs in one channel of such a calibration gas generator for a complex calibration in one sweep. As an example, a mixture of so-called “Signs of Life” – compounds available in the exhaled breath and/or in the sweat of everybody was used. The procedure of developing the appropriate mixture and the results of a successful calibration of a GC-ion mobility spectrometer are presented.

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Acknowledgments

The financial support of the Bundesministerium für Bildung und Forschung and the Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen is gratefully acknowledged. This research was funded by the European Union as part of the project “Detection of olfactory traces by orthogonal gas identification technologies” (DOGGIES), a collaborative project (No. 285446) funded under call identifier FP7-SEC-20011-1, which is part of the FP7 Program. Furthermore, the dedicated support of the workshops at ISAS, Dortmund, Germany and CNR-IMM, Bologna, Italy was indispensable for the success of the present study. Moreover, the steady and easy-going support by IAS, namely Martin Schmäh and his stuff is gratefully acknowledged.

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Authors and Affiliations

  1. TU Dortmund, Technical Biochemistry, Emil-Figge-Str. 66, 44227, Dortmund, Germany

    Igor Bergen & Oliver Kayser

  2. ION-GAS GmbH, Konrad-Adenauer-Allee 11, 44263, Dortmund, Germany

    Sascha Liedtke & Wolfgang Vautz

  3. Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V, Bunsen-Kirchhoff-Str. 11, 44139, Dortmund, Germany

    Stefanie Güssgen, Carolin Drees & Wolfgang Vautz

  4. Eye on Air B.V., The Gallery, Hengelosestraat 500, 7521, Enschede, AN, Netherlands

    Chandrasekhara Hariharan

Authors
  1. Igor Bergen
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  2. Sascha Liedtke
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  3. Stefanie Güssgen
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  4. Oliver Kayser
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  5. Chandrasekhara Hariharan
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  6. Carolin Drees
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  7. Wolfgang Vautz
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All authors significantly contributed and have given approval to the final version of the manuscript.

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Correspondence to Wolfgang Vautz.

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Bergen, I., Liedtke, S., Güssgen, S. et al. Calibration of complex mixtures in one sweep. Int. J. Ion Mobil. Spec. 21, 55–64 (2018). https://doi.org/10.1007/s12127-018-0236-0

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  • DOI: https://doi.org/10.1007/s12127-018-0236-0

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