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Nasal Eosinophilic Angiocentric Fibrosis with Orbital Extension

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Abstract

Eosinophilic angiocentric fibrosis (EAF) is an extremely rare, chronic, benign, idiopathic disorder that mostly affects the upper respiratory tract, particularly the nasal cavity, and features progressive submucosal perivascular fibrosis. To the best of our knowledge, only seven cases of EAF with orbital involvement have been reported. We report a case of sinonasal EAF with orbital extension that presented with left nasolacrimal duct obstruction. A 35-year-old man presented with left epiphora, proptosis, anterolateral globe displacement and nasal obstruction. Endoscopic sinus examination showed a firm, gritty, creamy, yellow, fibrous, adherent mass of maxillary sinus. Diagnosis was established with histopathological examination of excisional biopsy of the lesion. Although EAF is very rare, it should be considered in the differential diagnosis of lesions of upper airway tract, particularly the nasal cavity. Biopsy is necessary for diagnosis and treatment planning. Resecting of the involved tissues completely is essential for prevention of recurrence.

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Authors and Affiliations

  1. Department of Otorhinolaryngology Head and Neck Surgery, Shiraz University of Medical Sciences, Shiraz, Iran

    Mohammad Faramarzi

  2. Otorhinolaryngology Research Center, Department of Otorhinolaryngology-Head & Neck Surgery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Mohammad Hossein Dadgarnia & Nasim Behniafard

  3. Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Mansour Moghimi

  4. Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Hadi Sharouny

Authors
  1. Mohammad Faramarzi
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  2. Mohammad Hossein Dadgarnia
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  3. Mansour Moghimi
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  4. Hadi Sharouny
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  5. Nasim Behniafard
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Correspondence to Mohammad Faramarzi.

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Faramarzi, M., Dadgarnia, M.H., Moghimi, M. et al. Nasal Eosinophilic Angiocentric Fibrosis with Orbital Extension. Head and Neck Pathol 9, 426–429 (2015). https://doi.org/10.1007/s12105-014-0605-x

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  • DOI: https://doi.org/10.1007/s12105-014-0605-x

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