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Rotavirus Gastroenteritis Associated with Encephalopathy, Myositis, Transaminitis and Hypoalbuminemia

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Abstract

Rotavirus is a common cause of acute gastroenteritis in children. Manifestations of rotavirus gastroenteritis beyond gastrointestinal tract are rare. Rotavirus has been reported to be associated with encephalopathy, myositis and elevated liver enzymes; but simultaneous presentation of all these conditions in the same child is extremely rare. The authors report a case of 17-mo-old girl who presented with acute rotavirus gastroenteritis with G3 + G9P[8] strain associated with hypernatremia, encephalopathy, myositis, transaminitis and hypoalbuminemia. Child had complete recovery with no neurological sequalae on follow-up, and liver enzymes and albumin returned to normal. The authors suggest that rotavirus infection should be considered in the differential diagnosis of a child with encephalopathy or myositis, particularly if associated with acute diarrhea.

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Acknowledgements

Dr. Sidhartha Giri, Assistant Professor of Microbiology, Welcome Trust Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore – for conducting molecular studies on stool sample.

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Authors and Affiliations

  1. Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, 110095, India

    Maharshi Trivedi, Abhishek Jain, Dheeraj Shah & Piyush Gupta

Authors
  1. Maharshi Trivedi
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  2. Abhishek Jain
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  3. Dheeraj Shah
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  4. Piyush Gupta
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Contributions

MT and AJ: Collection of clinical and laboratory data, writing the manuscript; DS and PG: Writing the manuscript and review literature. DS is the guarantor for this article.

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Correspondence to Dheeraj Shah.

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Trivedi, M., Jain, A., Shah, D. et al. Rotavirus Gastroenteritis Associated with Encephalopathy, Myositis, Transaminitis and Hypoalbuminemia. Indian J Pediatr 86, 642–644 (2019). https://doi.org/10.1007/s12098-019-02959-8

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  • DOI: https://doi.org/10.1007/s12098-019-02959-8

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