Abstract
We report a case of prepubertal gynecomastia diagnosed during growth hormone (GH) treatment. In our patient gynecomastia appeared 6 months after GH was started. This condition appears to be self-limited and benign. In our patient gynaecomastia resolved on its own.
Similar content being viewed by others
References
Nydick M, Bustos J, Dale J, Rawson RW. Gynecomastia in adolescent boys. JAMA 1961; 178: 449–454.
Haibach H, Rosebholtz MJ. Prepubertal gynecomastia with lobules and acini: a case report and review of the literature. Am J Clin Pathol 1983; 80: 252–255.
Payne AH, Perkins LM, Giorgiou M, Quinn PG. Intratesticular aromatase site of activity and possible function of testicular estradiol. Steroids 1987; 50: 435–448.
Brodie A, Inkster S. Aromatase in the human testis. J Steroid Biochem Mol Biol 1993; 44: 549–555.
Rudman D, Feller AG, Cohn L, Shetty KR, Rudman IW, Draper MW. Effects of human growth hormone in body composition in elderly men. Horm Res 1991; 36: 73–81.
Murphy L J, Murphy LC, Stead B, Sutherland RL, Lazarus L. Modulation of lactogenic receptors by progestins in cultured human breast cancer cells. J Clin Endocrinol Metab 1986; 62: 280–287.
Descamps H, Chaussain JL, Job JC. Les gynecomasties du garcon avant la puberte. Arch Fr Pediatr 1985;42:87–89.
Saul Malozowski, Bruce V. Stadel. Prepubertal gynecomastia during growth hormone therapy. J Pediatr 1995; 126: 659–661.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Acharya, S.V., Gopal, R.A., Bandgar, T.R. et al. Prepubertal gynecomastia a rare complication of growth hormone therapy. Indian J Pediatr 77, 443–444 (2010). https://doi.org/10.1007/s12098-010-0012-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-010-0012-6