Skip to main content

Advertisement

Log in

Kimura’s Disease: A Confounding Condition

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Kimura disease (KD) is a chronic inflammatory lymphoproliferative disorder of unknown etiology and unsure pathogenesis. It primarily involves the head and neck region, presenting as an asymptomatic unilateral soft-tissue mass in the head and neck, frequently involving subcutaneous tissues, major salivary gland, lymph nodes. Peripheral blood eosinophilia, elevated serum immunoglobulin E (IgE) levels, and the microscopically lymphoid proliferation with eosinophilic infiltration are the characteristic features. We report a case of KD in a 22-year-old Indian male who presented with an asymptomatic parotid gland enlargement with lymphadenopathy. The clinical presentation was suggestive of the benign lesion but histopathology, as well as microscopic findings, allowed us to make a definitive diagnosis of KD. The patient was treated with steroids and antihistamine and showed no recurrence on follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Singh LS, Singh TS, Singh KL, Singh CA, Moirangthem GS (2014) Kimura’s disease of the parotid gland: a case report. Int J Sci Study 2:252–254

    CAS  Google Scholar 

  2. Afzan A, Kuantan P (2014) Kimura’s disease of the parotid: a complete clinical–radiological-pathology report. Med J Malaysia 69(4):199

    Google Scholar 

  3. Ranka SR, Rajput A, Kantharia CV (2004) Kimura’s disease. Indian J Otolaryngol Head Neck Surg 56(1):43

    Article  CAS  Google Scholar 

  4. Choi JA, Lee GK, Kong KY, Hong SH, Suh JS, Ahn JM, Lee YJ, Cho KH, Park JG, Choi JY, Kang HS (2005) Imaging findings of Kimura’s disease in the soft tissue of the upper extremity. Am J Roentgenol 184(1):193–199

    Article  Google Scholar 

  5. Takahashi S, Ueda J, Furukawa T, Tsuda M, Nishimura M, Orita H, Tsujimura T, Araki Y (1996) Kimura disease: CT and MR findings. Am J Neuroradiol 17(2):382–385

    CAS  Google Scholar 

  6. Osuch-Wójcikiewicz E, Bruzgielewicz A, Lachowska M, Wasilewska A, Niemczyk K (2014) Kimura’s disease in a caucasian female: a very rare cause of lymphadenopathy. Case Rep Otolaryngol. https://doi.org/10.1155/2014/415865

    Article  Google Scholar 

  7. Nehru VI, Abrol R, Vaiphei K, Singh P (2000) Kimura’s Disease—report of a case masquerading as a parotid tumor. Indian J Otolaryngol Head Neck Surg 52(3):302–304

    Article  CAS  Google Scholar 

  8. Larroche C, Bletry O (2005) Kimura’s disease. Orphanet encyclopedia.

  9. Watkin GT, MacLennan KA, Hobsley M (1984) Lymphomas presenting as lumps in the parotid region. Br J Surg 71(9):701–702

    Article  CAS  Google Scholar 

  10. Frankel AM, Frenkel S, Aminlari A, Chan T (2020) Kikuchi disease: a case report. J Emerg Med 59(6):927–930

    Article  Google Scholar 

  11. Tunkel DE, Loury MC, Goins MA III, Johns ME, Fox CH (1989) Bilateral parotid enlargement in HIV-seropositive patients. Laryngoscope 99(6):590–595

    Article  CAS  Google Scholar 

Download references

Acknowledgment

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sheetal Sharma.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Human and Animal Rights

Animals were not involved in the study.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Parikh, S., Sharma, S. & Shah, J.S. Kimura’s Disease: A Confounding Condition. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5342–5346 (2022). https://doi.org/10.1007/s12070-021-02511-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-021-02511-1

Keywords

Navigation