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Unusual Presentation of Malignant Peripheral Nerve Sheath Tumour of Mandible as a Colossal Tumour After Neoadjuvant Chemotherapy

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

The uniqueness of this case is the presentation of malignant peripheral nerve sheath tumors arising from the mandible as a colossal tumor of size of about 28 cm and weight of 1.5 kg after the first cycle of neoadjuvant chemotherapy. Role of neoadjuvant chemotherapy remains controversial and can be avoided if margin negative resection is feasible.

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Abbreviations

MPNST:

Malignant peripheral nerve sheath tumors

NF1:

Neurofibromatosis 1

NACT:

Neoadjuvant chemotherapy

IHC:

Immunohistochemistry

CT:

Computed tomography

LR:

Local recurrence

OS:

Overall survival

DM:

Distant metastasis

References

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Acknowledgement

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Authors and Affiliations

  1. Department Of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India

    Dipin Jayaprakash, Priyank Rathod, Supreet Bhatt & Ankit Sharma

Authors
  1. Dipin Jayaprakash
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  2. Priyank Rathod
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  3. Supreet Bhatt
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  4. Ankit Sharma
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Contributions

All authors contributed to the study conception and design. Material preparation was performed by Dipin and Priyank Rathod. The first draft of the manuscript was written by Dipin. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Priyank Rathod.

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Authors declare there is no conflict of interest.

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Informed consent was obtained.

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Authors affirm that patient informed consent for publication of the images and participant has consented to the submission of the case report to the journal.

Ethical Approval

This research study was conducted retrospectively from data obtained for clinical purposes. We consulted extensively with the IRB of the institute who determined that our study did not need ethical approval.

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The authors affirm that human research participants provided informed consent for publication of the images. The participant has consented to the submission of the case report to the journal.

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Jayaprakash, D., Rathod, P., Bhatt, S. et al. Unusual Presentation of Malignant Peripheral Nerve Sheath Tumour of Mandible as a Colossal Tumour After Neoadjuvant Chemotherapy. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5893–5896 (2022). https://doi.org/10.1007/s12070-021-02477-0

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  • DOI: https://doi.org/10.1007/s12070-021-02477-0

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