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Genomics of Lactic Acid Bacteria for Glycerol Dissimilation

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Abstract

Lactic acid bacteria (LAB) are functional starter cultures in food and dairy industry and are also regarded as power houses for bioprocess and fermentation technology. Due to extensive applications in food and medical applications, intensive research and developmental activities are going on throughout the world to understand the genomic and metabolic aspects during the past few decades. These LAB strains have significant role in production of value added chemicals and fuels from lignocellulosic biomass and other by-product streams establishing a circular bioeconomy. In this context, we discuss the physiology and genetics of crude glycerol dissimilation in lactic acid bacteria, the value added chemicals produced from biodiesel-derived crude glycerol. The overview of metabolic engineering strategies to improve the cellular traits and future perspectives in constructing cellulolytic/hemicellulolytic LAB strains to establish a renewable and sustainable cost-effective biorefinery is discussed.

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Acknowledgement

Narisetty Vivek acknowledges Department of Science and Technology (DST), New Delhi for DST-INSPIRE fellowship scheme for doctoral studies. Narisetty Vivek, Hazeena S H, Rajesh R O and Lakshmi M Nair acknowledge Academy of Scientific and Innovative Research (AcSIR) for providing resources to carry out doctoral studies. Raveendran Sindhu acknowledges the Department of Science and Technology for financial support under DST WOS-B scheme. Binod P and Kodakkattil Babu Anjali acknowledges CSIR for research grant under CSD-Mission project (HCP 0009) and Binod P, Lakshmi M Nair, Binoop Mohan, and Salini Chandrasekharan Nair acknowledges financial support by the Department of Science and Technology (DST), New Delhi under INNO-INDIGO/INDO-NORDEN project (Sanction No. DST/IMRCD/INNO-INDIGO/INDO-NORDEN/2017(G).

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  1. Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, 695019, India

    Narisetty Vivek, Sulfath Hakkim Hazeena, Rajendran Omana Rajesh, Tharangattumana Krishnan Godan, Kodakkattil Babu Anjali, Lakshmi M. Nair, Binoop Mohan, Salini Chandrasekharan Nair, Raveendran Sindhu & Parameswaran Binod

  2. Academy of Scientific and Innovative Research (AcSIR), New Delhi, India

    Narisetty Vivek, Sulfath Hakkim Hazeena, Rajendran Omana Rajesh & Lakshmi M. Nair

  3. Centre for Innovation and Translational Research, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), 31MG Marg, Lucknow, 226001, India

    Ashok Pandey

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Vivek, N., Hazeena, S.H., Rajesh, R.O. et al. Genomics of Lactic Acid Bacteria for Glycerol Dissimilation. Mol Biotechnol 61, 562–578 (2019). https://doi.org/10.1007/s12033-019-00186-2

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