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Ultrasound-guided percutaneous ethanol injection in papillary thyroid cancer metastatic lymph-nodes

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Abstract

Post-operative neck nodal metastases are detected in 9–20 % of papillary thyroid cancer (PTC). Ultrasound-guided ethanol injection (UPEI) has been used with promising results in the treatment of PTC patients with limited number of lymph-node metastases. Clinical Case: We report the imaging and biochemical documentation of UPEI results in four metastatic neck lymph-nodes of papillary thyroid-cancer. A significant reduction both in the diameter of the lymph-nodes and in the serum thyroglobulin levels were observed in all cases and have been reported in a step-by-step sequence. Conclusion: the UPEI treatment is a simple and suitable tool for the treatment of PTC cervical lymph-node metastases.

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References

  1. S.K. Grebe, I.D. Hay, Thyroid cancer nodal metastases: biologic significance and therapeutic considerations. Surg. Oncol. Clin. N. Am. 5, 43–63 (1996)

    PubMed  CAS  Google Scholar 

  2. K.G. Schuff, Management of recurrent/persistent papillary thyroid carcinoma: efficacy of the surgical option. J. Clin. Endocrinol. Metab. 96, 2038–2039 (2011)

    Article  PubMed  CAS  Google Scholar 

  3. J.H. Yim, W.B. Kim, E.Y. Kim, W.G. Kim, T.Y. Kim, J.S. Ryu, G. Gong, S.J. Hong, Y.K. Shong, The outcomes of first reoperation for locoregionally recurrent/persistent papillary thyroid carcinoma in patients who initially underwent total thyroidectomy and remnant ablation. J. Clin. Endocrinol. Metab. 96, 2049–2056 (2011)

    Article  PubMed  CAS  Google Scholar 

  4. B.D. Lewis, I.D. Hay, J.W. Charboneau, B. McIver, C.C. Reading, J.R. Goellner, Percutaneous ethanol injection for treatment of cervical lymph node metastases in patients with papillary thyroid carcinoma. AJR Am. J. Roentgenol. 178, 699–704 (2002)

    Article  PubMed  CAS  Google Scholar 

  5. J.M. Monchik, G. Donatini, J. Iannuccilli, D.E. Dupuy, Radiofrequency ablation and percutaneous ethanol injection treatment for recurrent local and distant well-differentiated thyroid carcinoma. Ann. Surg. 244, 296–304 (2006)

    Article  PubMed  PubMed Central  Google Scholar 

  6. C.Y. Lim, J.S. Yun, J. Lee, K.H. Nam, W.Y. Chung, C.S. Park, Percutaneous ethanol injection therapy for locally recurrent papillary thyroid carcinoma. Thyroid 17, 347–350 (2007)

    Article  PubMed  CAS  Google Scholar 

  7. B.M. Kim, M.J. Kim, E.K. Kim, S.I. Park, C.S. Park, W.Y. Chung, Controlling recurrent papillary thyroid carcinoma in the neck by ultrasonography-guided percutaneous ethanol injection. Eur. Radiol. 18, 835–842 (2008)

    Article  PubMed  Google Scholar 

  8. A. Heilo, E. Sigstad, K.H. Fagerlid, O.I. Håskjold, K.K. Grøholt, A. Berner, T. Bjøro, L.H. Jørgensen, Efficacy of ultrasound-guided percutaneous ethanol injection treatment in patients with a limited number of metastatic cervical lymph nodes from papillary thyroid carcinoma. J. Clin. Endocrinol. Metab. 96, 2750–2755 (2011)

    Article  PubMed  CAS  Google Scholar 

  9. Y.M. Sohn, S.W. Hong, E.K. Kim, M.J. Kim, H.J. Moon, S.J. Kim, E.J. Son, J.Y. Kwak, Complete eradication of metastatic lymph node after percutaneous ethanol injection therapy: pathologic correlation. Thyroid 19, 317–319 (2009)

    Article  PubMed  Google Scholar 

  10. I.D. Hay, R.A. Lee, C. Davidge-Pitts, C.C. Reading, J.W. Charboneau, Long-term outcome of ultrasound-guided percutaneous ethanol ablation of selected “recurrent” neck nodal metastases in 25 patients with TNM stages III or IVA papillary thyroid carcinoma previously treated by surgery and 131I therapy. Surgery 154(6), 1448–1454 (2013)

    Article  PubMed  Google Scholar 

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Endocrine Unit, Fondazione IRCCS Cà Granda, Milan and Department of Clinical Sciences and Community Health, University of Milan, Via Sforza, 35, 20122, Milan, Italy

    Guia Vannucchi, Danila Covelli, Michela Perrino, Simone De Leo & Laura Fugazzola

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  1. Guia Vannucchi
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  2. Danila Covelli
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  3. Michela Perrino
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  4. Simone De Leo
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  5. Laura Fugazzola
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Correspondence to Guia Vannucchi.

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Vannucchi, G., Covelli, D., Perrino, M. et al. Ultrasound-guided percutaneous ethanol injection in papillary thyroid cancer metastatic lymph-nodes. Endocrine 47, 648–651 (2014). https://doi.org/10.1007/s12020-014-0215-0

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  • DOI: https://doi.org/10.1007/s12020-014-0215-0

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