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The Study on the Correlation Between Six Kinds of Mineral Elements and Diabetes

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Abstract

The study aimed to explore the relationship of six kinds of mineral elements and diabetes among adults in northeast China. A cross-sectional survey was conducted in Jilin Province, northeast China. A total of 366 males and 204 females aged 18 ~ 77 years from Jingyu town, Dongliao town, and Changling town were included using a multistage stratified random cluster sampling design. Data was obtained from face to face interview, physical examination, and laboratory measurement. We defined the normal people (3.9 ~ 6.0 mmol/L), impaired fasting glucose (IFG) individuals (6.1 ~ 6.9 mmol/L), and diabetes mellitus (DM) (> 7.0 mmol/L) according to the WHO diagnostic criteria. Kruskal-Wallis test, Spearman rank correlation, as well as binary logistic regression were used to analyze influencing factors. lg(Cu/Zn)was correlated with DM (OR 8.390; 95% CI of OR 1.272–55.347). The specific mineral elements such as Zn, Ca, as well as Cu/Zn ratio may be the potential risk factors for diabetes. So, the supplement or reduction of these elements is supposed to be told to IFG to prevent or delay the occurrence of diabetes or DM to avoid its complication.

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Acknowledgements

We thank all participants involved in this study.

Funding Information

This work was supported by the Scientific Research Foundation of the Health Bureau of Jilin Province, China (grant number: 2011Z116).

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Authors and Affiliations

  1. Department of Epidemiology and Biostatistics, Jilin University School of Public Health, Changchun, China

    Zhuo Li, Changcong Wang, Lu Li, Mengyun Shao, Linbo Wang, Xin Lv, Chunshi Gao, Huikun Niu & Bo Li

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  1. Zhuo Li
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  2. Changcong Wang
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  3. Lu Li
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  9. Bo Li
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Contributions

ZL, BL, and CW conceived and designed the experiments; ZL, CW, LL, LW, and MS performed the experiments; ZL, CW, CG, XL, and HN analyzed the data and drafted the manuscript; ZL, CW, and BL participated in revising the manuscript together. All authors approved the final version of the manuscript.

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Correspondence to Bo Li.

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Li, Z., Wang, C., Li, L. et al. The Study on the Correlation Between Six Kinds of Mineral Elements and Diabetes. Biol Trace Elem Res 183, 226–232 (2018). https://doi.org/10.1007/s12011-017-1136-6

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