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Selenium Supplementation Changes the Ion Profile in the Pancreas of Chickens Treated with Cadmium

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Abstract

Increasing evidence indicates that selenium (Se) could antagonize metal toxicity, including cadmium (Cd) toxicity. However, the effects of Se on Cd-induced changes in the ion profile in the pancreas of chickens have not been reported. In the present study, 128 Hy-Line brown laying chickens were divided into the control group, Se-treated group, Se/Cd-treated group, and Cd-treated group, and we detected the concentrations of 28 ions in the four groups by inductively coupled plasma mass spectrometry. In the Cd-treated group, the accumulation of Cd in the pancreas was 836.8 times higher that than in the control group (27,353.71 ppb/32.69 ppb). Meanwhile, the Ca, Ti, Fe, Mo, Li, Al, and Pb levels increased and the Cr, Mn, Ni, Cu, Zn, Se, Sr, and Sb levels decreased due to sub-chronic Cd poisoning. The Fe, Mo, Ba, and Pb levels decreased in the Se/Cd-treated group. Our findings suggest that Cd can accumulate in the chicken pancreas and affect the ion profiles, whereas Se can ameliorate the accumulation of Cd and change the ion profiles in the chicken pancreas.

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Acknowledgments

This study was supported by the Science Foundation of the Education Department of Heilongjiang Province (Grant No.11551030).

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Authors and Affiliations

  1. College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People’s Republic of China

    Rongkun Bao, Shufang Zheng, Qiaojian Zhang, Hongjin Lin & Shu Li

  2. College of Life Science, Northeast Agricultural University, Harbin, 150030, People’s Republic of China

    Xinyue Wang

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  1. Rongkun Bao
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  2. Xinyue Wang
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Correspondence to Hongjin Lin or Shu Li.

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All procedures used in this study were approved by the Institutional Animal Care and Use Committee of Northeast Agricultural University.

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Bao, R., Wang, X., Zheng, S. et al. Selenium Supplementation Changes the Ion Profile in the Pancreas of Chickens Treated with Cadmium. Biol Trace Elem Res 181, 133–141 (2018). https://doi.org/10.1007/s12011-017-1034-y

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