Abstract
Room temperatures ionic liquids are considered as miraculous solvents for biological system. Due to their inimitable properties and large variety of applications, they have been widely used in enzyme catalysis and protein stability and separation. The related information present in the current review is helpful to the researchers working in the field of biotechnology and biochemistry to design or choose an ionic liquid that can serve as a noble and selective solvent for any particular enzymatic reaction, protein preservation and other protein based applications. We have extensively analyzed the methods used for studying the protein–IL interaction which is useful in providing information about structural and conformational dynamics of protein. This can be helpful to develop and understanding about the effect of ionic liquids on stability and activity of proteins. In addition, the affect of physico-chemical properties of ionic liquids, viz. hydrogen bond capacity and hydrophobicity on protein stability are discussed.
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References
Klibanov, A. M. (1983). Advances in Applied Microbiology, 29, 1–28.
Illanes, A. (1999). Electronic Journal of Biotechnology, 2, 1–9.
Volkin, D. B., & Klibanov, A. M. (1989). Protein function: practical approach. Oxford: IRL Press.
Kaushik, J. K., & Bhat, R. (1998). The Journal of Physical Chemistry B, 102, 7058–7066.
Santoro, M. M., Liu, Y., Khan, S. M., Hou, L. X., & Bolen, D. W. (1992). Biochemistry, 31, 5278–5283.
Arakawa, T., Bhat, R., & Timasheff, S. N. (1990). Biochemistry, 29, 1924–1931.
Vrikkis, R. M., Fraser, K. J., Fujita, K., Macfarlane, D. R., & Elliott, G. D. (2009). Journal of Biomechanical Engineering, 131, 074514.
Dabirmanesh, B., Khajeh, K., Ranjbar, B., Ghazi, F., & Heydari, A. (2012). Journal of Molecular Liquids, 170, 66–71.
Dang, D. T., Ha, S. H., Lee, S. M., Chang, W. J., & Koo, Y. M. (2007). Journal of Molecular Catalysis B: Enzymatic, 45, 118–121.
Persson, M., & Bornscheuer, U. T. (2003). Journal of Molecular Catalysis B: Enzymatic, 22, 21–27.
Buchfink, R., Tischer, A., Patil, G., Rudolph, R., & Lange, C. (2010). Journal of Biotechnology, 150, 64–72.
Lozano, P., De Diego, T., Carrie, D., Vaultier, M., & Iborra, J. L. (2001). Biotechnology Letters, 23, 1529–1533.
Gordon, C. M. (2001). Applied Catalysis A: General, 222, 101–117.
Houlton, S. (2004). Chemical Week, 10–11.
Seddon, K. R. (1997). Journal of Chemical Technology & Biotechnology, 68, 351–356.
Welton, T. (1999). Chemical Reviews, 99, 2071–2084.
Freemantle, M. (1998). Chemical & Engineering News Archive, 76, 32–37.
Sate, D., Janssen, M. H. A., Stephens, G., Sheldon, R. A., Seddon, K. R., & Lu, J. R. (2007). Green Chemistry, 9, 859–867.
De Diego, T., Lozano, P., Gmouh, S., Vaultier, M., & Iborra, J. L. (2005). Biomacromolecules, 6, 1457–1464.
Baker, S. N., McCleskey, T. M., Pandey, S., & Baker, G. A. (2004). Chemical Communications, 0, 940–941.
Lozano, P., De Diego, T., Gmouh, S., Vaultier, M., & Iborra, J. L. (2005). Biocatalysis and Biotransformation, 23, 169–176.
Zhao, H. (2005). Journal of Molecular Catalysis B: Enzymatic, 37, 16–25.
Wiggins, P. M. (1997). Physica A: Statistical Mechanics and its Applications, 238, 113–128.
Collins, K. D. (2004). Methods, 34, 300–311.
Baldwin, R. L. (1996). Biophysical Journal, 71, 2056–2063.
Jain, N., Kumar, A., Chauhan, S., & Chauhan, S. M. S. (2005). Tetrahedron, 61, 1015–1060.
Dupont, J. (2004). Journal of the Brazilian Chemical Society, 15, 341–350.
Schroder, U., Wadhawan, J. D., Compton, R. G., Marken, F., Suarez, P. A. Z., Consorti, C. S., de Souza, R. F., & Dupont, J. (2000). New Journal of Chemistry, 24, 1009–1015.
MacFarlane, D. R., Pringle, J. M., Johansson, K. M., Forsyth, S. A., & Forsyth, M. (2006). Chemical Communications, 0, 1905–1917.
Rogers, R. D., Seddon, K. R., & Volkov, S. (Eds.). (2002). Kluwer Academic Publisher, Dordrecht, Netherlands. pp. 105–107.
Zhao, H. (2010). Journal of Chemical Technology & Biotechnology, 85, 891–907.
Anderson, J. L., Ding, J., Welton, T., & Armstrong, D. W. (2002). Journal of the American Chemical Society, 124, 14247–14254.
Armstrong, D. W., He, L., & Liu, Y. S. (1999). Analytical Chemistry, 71, 3873–3876.
Park, S., & Kazlauskas, R. J. (2003). Current Opinion in Biotechnology, 14, 432–437.
Sheldon, R. A., Lau, R. M., Sorgedrager, M. J., van Rantwijk, F., & Seddon, K. R. (2002). Green Chemistry, 4, 147–151.
Lozano, P., de Diego, T., Guegan, J.-P., Vaultier, M., & Iborra, J. L. (2001). Biotechnology and Bioengineering, 75, 563–569.
Zhao, H., Olubajo, O., Song, Z., Sims, A. L., Person, T. E., Lawal, R. A., & Holley, L. A. (2006). Bioorganic Chemistry, 34, 15–25.
Lue, B.-M., Guo, Z., & Xu, X. (2010). Process Biochemistry, 45, 1375–1382.
Kaar, J. L., Jesionowski, A. M., Berberich, J. A., Moulton, R., & Russell, A. J. (2003). Journal of the American Chemical Society, 125, 4125–4131.
Heller, W. T., O’Neill, H. M., Zhang, Q., & Baker, G. A. (2010). Journal of Physical Chemistry B, 114, 13866–13871.
Turner, M. B., Spear, S. K., Huddleston, J. G., Holbrey, J. D., & Rogers, R. D. (2003). Green Chemistry, 5, 443–447.
Noritomi, H., Minamisawa, K., Kamiya, R., & Kato, S. (2011). Journal of Biomedical Science and Engineering, 4, 94–99.
Lee, S., Ha, S., Lee, S., & Koo, Y. M. (2006). Biotechnology Letters, 28, 1335–1339.
Dabirmanesh, B., Daneshjou, S., Sepahi, A. A., Ranjbar, B., Khavari-Nejad, R. A., Gill, P., Heydari, A., & Khajeh, K. (2011). International Journal of Biological Macromolecules, 48, 93–97.
Constantinescu, D., Herrmann, C., & Weingartner, H. (2010). Physical Chemistry Chemical Physics, 12, 1756–1763.
Madeira Lau, R., Sorgedrager, M. J., Carrea, G., van Rantwijk, F., Secundo, F., & Sheldon, R. A. (2004). Green Chemistry, 6, 483–487.
Hernandez-Fernandez, F. J., Rios, A. P. D. I., Tomas-Alonso, F., Gomez, D., & Víllora, G. (2009). Canadian Journal of Chemical Engineering, 87, 910–914.
Zhao, H., Baker, G. A., Song, Z., Olubajo, O., Crittle, T., & Peters, D. (2008). Green Chemistry, 10, 696–705.
Toral, A. R., de los Rios, A. P., Hernandez, F. J., Janssen, M. H., Schoevaart, R., van Rantwijk, F., & Sheldon, R. A. (2007). Enzyme and Microbial Technology, 40, 1095–1099.
Zhao, H., Baker, G. A., Song, Z., Olubajo, O., Zanders, L., & Campbell, S. M. (2009). Journal of Molecular Catalysis B: Enzymatic, 57, 149–157.
Wolski, P. W., Clark, D. S., & Blanch, H. W. (2011). Green Chemistry, 13, 3107–3110.
Klahn, M., Lim, G. S., & Wu, P. (2011). Physical Chemistry Chemical Physics, 13, 18647–18660.
Tavares, A. P. M., Rodriguez, O., & Macedo, E. A. (2008). Biotechnology and Bioengineering, 101, 201–207.
Irimescu, R., & Kato, K. (2004). Journal of Molecular Catalysis B: Enzymatic, 30, 189–194.
Lee, S., Koo, Y.-M., & Ha, S. (2008). Korean Journal of Chemical Engineering, 25, 1456–1462.
Yang, Z. (2009). Journal of Biotechnology, 144, 12–22.
Yamamoto, E., Yamaguchi, S., & Nagamune, T. (2011). Applied Biochemistry and Biotechnology, 164, 957–967.
Attri, P., Venkatesu, P., & Kumar, A. (2011). Physical Chemistry Chemical Physics, 13, 2788–2796.
Laszlo, J. A., & Compton, D. L. (2001). Biotechnology and Bioengineering, 75, 181–186.
Yang, Z., & Pan, W. (2005). Enzyme and Microbial Technology, 37, 19–28.
Erbeldinger, M., Mesiano, A. J., & Russell, A. J. (2000). Biotechnology Progress, 16, 1129–1131.
Nara, S. J., Harjani, J. R., & Salunkhe, M. M. (2002). Tetrahedron Letters, 43, 2979–2982.
de Gonzalo, G., Lavandera, I., Durchschein, K., Wurm, D., Faber, K., & Kroutil, W. (2007). Tetrahedron: Asymmetry, 18, 2541–2546.
Paljevac, M., Habulin, M., & Knez, Z. (2006). Chemical Industry and Chemical Engineering Quarterly, 12, 181–186.
Shen, Z. L., Zhou, W. J., Liu, Y. T., Ji, S. J., & Loh, T. P. (2008). Green Chemistry, 10, 283–286.
Nakashima, K., Okada, J., Maruyama, T., Kamiya, N., & Goto, M. (2006). Science and Technology of Advanced Materials, 7, 692–698.
Zhang, W. G., Wei, D. Z., Yang, X. P., & Song, Q. X. (2006). Bioprocess and Biosystems Engineering, 29, 379–383.
De Los Rios, A. P., Hernandez-Fernandez, F. J., Martínez, F. A., Rubio, M., & Víllora, G. (2007). Biocatalysis and Biotransformation, 25, 151–156.
Ryu, K., & Dordick, J. S. (1992). Biochemistry, 31, 2588–2598.
Lou, W.-Y., Zong, M.-H., Wu, H., Xu, R., & Wang, J.-F. (2005). Green Chemistry, 7, 500–506.
Eggers, D. K., & Valentine, J. S. (2001). Journal of Molecular Biology, 314, 911–922.
Collins, K. D. (1997). Biophysical Journal, 72, 65–76.
Zhang, Y., Furyk, S., Bergbreiter, D. E., & Cremer, P. S. (2005). Journal of the American Chemical Society, 127, 14505–14510.
Sedlak, E., Stagg, L., & Wittung-Stafshede, P. (2008). Archives of Biochemistry and iophysics, 479, 69–73.
Leberman, R., & Soper, A. K. (1995). Nature, 378, 364–366.
Collins, K. D., Neilson, G. W., & Enderby, J. E. (2007). Biophysical Chemistry, 128, 95–104.
Baker, S. N., Zhao, H., Pandey, S., Heller, W. T., Bright, F. V., & Baker, G. A. (2011). Physical Chemistry Chemical Physics, 13, 3642–3644.
Yang, Z., Yue, Y. J., Huang, W. C., Zhuang, X. M., Chen, Z. T., & Xing, M. (2009). Journal of Biochemistry, 145, 355–364.
Jenkins, H. D. B., & Marcus, Y. (1995). Chemical Reviews, 95, 2695–2724.
Collins, K. D., & Washabaugh, M. W. (1985). Quarterly Reviews of Biophysics, 18, 323–422.
Von Hippel, P. H., & Schleich, T. (1969). Accounts of Chemical Research, 2, 257–265.
Hochachka, P. W., & Somero, G. N. (2002). Biochemical adaptation: mechanism and process in physiological evolution. New York: Oxford University Press.
Fujita, K., MacFarlane, D. R., Forsyth, M., Yoshizawa-Fujita, M., Murata, K., Nakamura, N., & Ohno, H. (2007). Biomacromolecules, 8, 2080–2086.
Constantinescu, D., Weingartner, H., & Herrmann, C. (2007). Angewandte Chemie International Edition, 46, 8887–8889.
Weingartner, H., Cabrele, C., & Herrmann, C. (2012). Physical Chemistry Chemical Physics, 14, 415–426.
Lai, J. Q., Li, Z., Lu, Y. H., & Yang, Z. (2011). Green Chemistry, 13, 1860–1868.
Rodrigues, J. V., Prosinecki, V., Marrucho, I., Rebelo, L. P. N., & Gomes, C. M. (2011). Physical Chemistry Chemical Physics, 13, 13614–13616.
Yu, X., Zou, F., Li, Y., Lu, L., Huang, X., & Qu, Y. (2013). International Journal of Biological Macromolecules, 56, 62–68.
Grossfield, A., Ren, P., & Ponder, J. W. (2003). Journal of the American Chemical Society, 125, 15671–15682.
Combariza, J. E., Kestner, N. R., & Jortner, J. (1994). Journal of Chemical Physics, 100, 2851–2864.
Kaftzik, N., Wasserscheid, P., & Kragl, U. (2002). Organic Process Research & Development, 6, 553–557.
Lang, M., Kamrat, T., & Nidetzky, B. (2006). Biotechnology and Bioengineering, 95, 1093–1100.
Zhao, H. (2006). Journal of Chemical Technology & Biotechnology, 81, 871–891.
Van Rantwijk, F., & Sheldon, R. A. (2007). Chemical Reviews, 107, 2757–2785.
Tariq, M., Carvalho, P. J., Coutinho, J. A. P., Marrucho, I. M., Lopes, J. N. C., & Rebelo, L. P. N. (2011). Fluid Phase Equilibria, 301, 22–32.
Greaves, T. L., Weerawardena, A., Fong, C., Krodkiewska, I., & Drummond, C. J. (2006). Journal of Physical Chemistry B, 110, 22479–22487.
Yan, H., Wu, J., Dai, G., Zhong, A., Chen, H., Yang, J., & Han, D. (2012). Journal of Luminescence, 132, 622–628.
Ajloo, D., Sangian, M., Ghadamgahi, M., Evini, M., & Saboury, A. A. (2013). International Journal of Biological Macromolecules, 55, 47–61.
Ou, G., Yang, J., He, B., & Yuan, Y. (2011). Journal of Molecular Catalysis B: Enzymatic, 68, 66–70.
Lange, C., Patil, G., & Rudolph, R. (2005). Protein Science, 14, 2693–2701.
Attri, P., & Venkatesu, P. (2013). Process Biochemistry, 48, 462–470.
Lou, W. Y., & Zong, M. H. (2006). Chirality, 18, 814–821.
Fujita, K., MacFarlane, D. R., & Forsyth, M. (2005). Chemical Communications, 0, 4804–4806.
Micaelo, N. M., & Soares, C. M. (2008). Journal of Physical Chemistry B, 112, 2566–2572.
Byrne, N., Wang, L. M., Belieres, J. P., & Angell, C. A. (2007). Chemical Communications, 0, 2714–2716.
Laszlo, J. A., & Compton, D. L. (2002). Journal of Molecular Catalysis B: Enzymatic, 18, 109–120.
Dang, L., Fang, W., Li, Y., Qian Wang, Q., Hua-Zhi Xiao, H., & Wang, Z. (2013). Applied Biochemistry and Biotechnology, 169, 290–300.
Garlitz, J. A., Summers, C. A., Flowers, R. A., II, & Borgstahl, G. E. O. (1999). Acta Crystallographica Section D, 55, 2037–2038.
Hekmat, D., Hebel, D., Joswig, S., Schmidt, M., & Weuster-Botz, D. (2007). Biotechnology Letters, 29, 1703–1711.
Pusey, M. L., Paley, M. S., Turner, M. B., & Rogers, R. D. (2007). Crystal Growth & Design, 7, 787–793.
Judge, R. A., Takahashi, S., Longenecker, K. L., Fry, E. H., Abad-Zapatero, C., & Chiu, M. L. (2009). Crystal Growth & Design, 9, 3463–3469.
Wang, Z., Dang, L., Han, Y., Jiang, P., & Wei, H. (2010). Journal of Agricultural and Food Chemistry, 58, 5444–5448.
Coelho, C., Trincao, J., & Joao Romao, M. (2010). Journal of Crystal Growth, 312, 714–719.
Kennedy, D. F., Drummond, C. J., Peat, T. S., & Newman, J. (2011). Crystal Growth & Design, 11, 1777–1785.
Chen, X., Ji, Y., & Wang, J. (2010). Analyst, 135, 2241–2248.
Wang, Q., Baker, G. A., Baker, S. N., & Colon, L. A. (2006). Analyst, 131, 1000–1005.
Vidal, S. T. M., Neiva Correia, M. J., Marques, M. M., Ismael, M. R., & Angelino Reis, M. T. (2005). Separation Science and Technology, 39, 2155–2169.
Fan, J., Fan, Y., Pei, Y., Wu, K., Wang, J., & Fan, M. (2008). Separation and Purification Technology, 61, 324–331.
Abdolmohammad-Zadeh, H., & Sadeghi, G. H. (2009). Analytica Chimica Acta, 649, 211–217.
Manzoori, J. L., Amjadi, M., & Abulhassani, J. (2009). Analytica Chimica Acta, 644, 48–52.
Li, S., Cai, S., Hu, W., Chen, H., & Liu, H. (2009). Spectrochimica Acta Part B: Atomic Spectroscopy, 64, 666–671.
Yao, C., & Anderson, J. (2009). Analytical and Bioanalytical Chemistry, 395, 1491–1502.
Smirnova, S., Torocheshnikova, I., Formanovsky, A., & Pletnev, I. (2004). Analytical and Bioanalytical Chemistry, 378, 1369–1375.
Lo, W. H., Yang, H. Y., & Wei, G. T. (2003). Green Chemistry, 5, 639–642.
Abulhassani, J., Manzoori, J. L., & Amjadi, M. (2010). Journal of Hazardous Materials, 176, 481–486.
Du, Z., Yu, Y. L., & Wang, J. H. (2007). Chemistry - A European Journal, 13, 2130–2137.
Ge, L., Wang, X. T., Tan, S. N., Tsai, H. H., Yong, J. W. H., & Hua, L. (2010). Talanta, 81, 1861–1864.
Matsumoto, M., Ohtani, T., & Kondo, K. (2007). Journal of Membrane Science, 289, 92–96.
Cheng, D. H., Chen, X. W., Shu, Y., & Wang, J. H. (2008). Talanta, 75, 1270–1278.
Alvarez-Guerra, E., & Irabien, A. (2012). Separation and Purification Technology, 98, 432–440.
Dreyer, S., & Kragl, U. (2008). Biotechnology and Bioengineering, 99, 1416–1424.
Deive, F. J., Rodriguez, A., Rebelo, L. P. N., & Marrucho, I. M. (2012). Separation and Purification Technology, 97, 205–210.
Shu, Y., Chen, X.-W., & Wang, J.-H. (2010). Talanta, 81, 637–642.
Shu, Y., Han, L., Wang, X., Chen, X., & Wang, J. (2013). ACS Applied Materials & Interfaces, 5, 12156–12162.
Meng, H., Chen, X. W., & Wang, J. H. (2010). Nanotechnology, 21, 385704.
Meng, H., Chen, X. W., & Wang, J. H. (2011). Journal of Materials Chemistry, 21, 14857–14863.
Han, L., Shu, Y., Wang, X., Chen, X., & Wang, J. (2013). Analytical and Bioanalytical Chemistry, 405, 8799–8806.
Chen, X., Liu, J., & Wang, J. (2010). Analytical Methods, 2, 1222–1226.
Zhang, T., Gai, Q., Qu, F., & Zhang, Y. (2011). Electrophoresis, 32, 2904–2910.
Wei, W., & Danielson, N. D. (2011). Biomacromolecules, 12, 290–297.
Chitta, K. R., Van Meter, D. S., & Stalcup, A. M. (2010). Analytical and Bioanalytical Chemistry, 396, 775–781.
Corradini, D., Nicoletti, I., & Bonn, G. K. (2009). Electrophoresis, 30, 1869–1876.
Li, D., Wang, Z., Wang, L., Qu, C., & Zhang, H. (2009). Chromatographia, 70, 825–830.
Wu, X., Wei, W., Su, Q., Xu, L., & Chen, G. (2008). Electrophoresis, 29, 2356–2362.
El Rassi, Z. (2010). Electrophoresis, 31, 174–191.
Kasicka, V. (2010). Electrophoresis, 31, 122–146.
Wasserscheid, P., & Keim, W. (2000). Angewandte Chemie International Edition, 39, 3772–3789.
Larsen, A. S., Holbrey, J. D., Tham, F. S., & Reed, C. A. (2000). Journal of the American Chemical Society, 122, 7264–7272.
Van Rantwijk, F., Madeira Lau, R., & Sheldon, R. A. (2003). Trends in Biotechnology, 21, 131–138.
Wu, X., Zhao, B., Wu, P., Zhang, H., & Cai, C. (2009). Journal of Physical Chemistry B, 113, 13365–13373.
Zhao, H., Jackson, L., Song, Z., & Olubajo, O. (2006). Tetrahedron: Asymmetry, 17, 1549–1553.
Hong, E., Yoo, I. K. and Ryu, R. K. (2008). Proc. world congress on engineering and computer science, San Francisco, USA.
Moniruzzaman, M., Kamiya, N., & Goto, M. (2008). Langmuir, 25, 977–982.
De Diego, T., Lozano, P., Gmouh, S., Vaultier, M., & Iborra, J. L. (2004). Biotechnology and Bioengineering, 88, 916–924.
Ulbert, O., Belafi-Bako, K., Tonova, K., & Gubicza, L. (2005). Biocatalysis and Biotransformation, 23, 177–183.
Zhang, J., Lei, J., Liu, Y., Zhao, J., & Ju, H. (2009). Biosensors and Bioelectronics, 24, 1858–1863.
Karbalaei-Heidari, R. H., Shahbazi, M., & Absalan, G. (2013). Applied Biochemistry and Biotechnology, 170, 573–586.
Schofer, S. H., Kaftzik, N., Wasserscheid, P., Kragl, U. (2001). Chemical Communications, 5, 425–426.
Madeira Lau, R., Van Rantwijk, F., Seddon, K. R., & Sheldon, R. A. (2000). Organic Letters, 2, 4189–4191.
Kim, K. W., Song, B., Choi, M. Y., & Kim, M. J. (2001). Organic Letters, 3, 1507–1509.
Husum, T. L., Jorgensen, C. T., Christensen, M. W., & Kirk, O. (2001). Biocatalysis and Biotransformation, 19, 331–338.
Park, S., & Kazlauskas, R. J. (2001). Journal of Organic Chemistry, 66, 8395–8840.
Yuan, Y., Bai, S., & Sun, Y. (2006). Food Chemistry, 97, 324–330.
Wang, J., Sun, G. X., Yu, L., Wu, F. A., & Guo, X. J. (2013). Bioresource Technology, 128, 156–163.
Chen, W. J., Lou, W. Y., Yu, C. Y., Wu, H., Zong, M. H., & Smith, T. J. (2012). Journal of Biotechnology, 162, 183–190.
Attri, P., & Venkatesu, P. (2012). Journal of Chemical Thermodynamics, 52, 78–88.
Shu, Y., Liu, M., Chen, S., Chen, X., & Wang, J. (2011). Journal of Physical Chemistry B, 115, 12306–12314.
Mester, P., Wagner, M., & Rossmanith, P. (2010). Analytical and Bioanalytical Chemistry, 397, 1763–1766.
Geng, F., Zheng, L., Liu, J., Yu, L., & Tung, C. (2009). Colloid and Polymer Science, 287, 1253–1259.
Geng, F., Zheng, L., Yu, L., Li, G., & Tung, C. (2010). Process Biochemistry, 45, 306–311.
Debnath, S., Das, D., Dutta, S., & Das, P. K. (2010). Langmuir, 26, 4080–4086.
Akdogan, Y., Junk, M. J. N., & Hinderberger, D. (2011). Biomacromolecules, 12, 1072–1079.
Baker, G. A., & Heller, W. T. (2009). Chemical Engineering Journal, 147, 6–12.
Pandey, S. (2006). Analytica Chimica Acta, 556, 38–45.
Summers, C. A., & Flowers, R. A. (2000). Protein Science, 9, 2001–2008.
Mangialardo, S., Gontrani, L., Leonelli, F., Caminiti, R., & Postorino, P. (2012). RSC Advances, 2, 12329–12336.
Turner M.B., Holbrey J.D., Spear S.K., Pusey M.L., Rogers R.D. (2005). Effect of oxygen containing functional groups on protein stability in ionic liquid solutions. Ionic Liquids IIIB:Fundamentals, Progress, Challenges and Opportunities -Transformations and Processes, 902, 233–243.
Machado, M., & Saraiva, J. (2005). Biotechnology Letters, 27, 1233–1239.
Pavlidis, I. V., Gournis, D., Papadopoulos, G. K., & Stamatis, H. (2009). Journal of Molecular Catalysis B: Enzymatic, 60, 50–56.
Lee, J. K., & Kim, M. J. (2002). Journal of Organic Chemistry, 67, 6845–6847.
Gelamo, E. L., & Tabak, M. (2000). Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 56, 2255–2271.
Sandoval, M., Cortes, A., Civera, C., Trevino, J., Ferreras, E., Vaultier, M., Berenguer, J., Lozano, P., & Hernaiz, M. J. (2012). RSC Advances, 2, 6306–6314.
Byler, D. M., & Susi, H. (1986). Biopolymers, 25, 469–487.
Pelton, J. T., & McLean, L. R. (2000). Analytical Biochemistry, 277, 167–176.
Surewicz, W. K., & Mantsch, H. H. (1988). Biochimica et Biophysica Acta, 952, 115–130.
Maiti, N. C., Apetri, M. M., Zagorski, M. G., Carey, P. R., & Anderson, V. E. (2004). Journal of the American Chemical Society, 126, 2399–2408.
Van Wart, H. E., Lewis, A., Scheraga, H. A., & Saeva, F. D. (1973). Proceedings of the National Academy of Sciences, 70, 2619–2623.
Siamwiza, M. N., Lord, R. C., Chen, M. C., Takamatsu, T., Harada, I., Matsuura, H., & Shimanouchi, T. (1975). Biochemistry, 14, 4870–4876.
Mann, J. P., McCluskey, A., & Atkin, R. (2009). Green Chemistry, 11, 785–792.
Weaver, K. D., Vrikkis, R. M., Van Vorst, M. P., Trullinger, J., Vijayaraghavan, R., Foureau, D. M., McKillop, I. H., MacFarlane, D. R., Krueger, J. K., & Elliott, G. D. (2012). Physical Chemistry Chemical Physics, 14, 790–801.
Fan, Y., Yan, J., Zhang, S., Li, J., Chen, D., Duan, P. (2012). Applied Biochemistry and Biotechnology, 168, 592–603.
Bowman, W. A., Rubinstein, M., & Tan, J. S. (1997). Macromolecules, 30, 3262–3270.
Singh, T., Boral, S., Bohidar, H. B., & Kumar, A. (2010). Journal of Physical Chemistry B, 114, 8441–8448.
Cooper, A. (1999). Current Opinion in Chemical Biology, 3, 557–563.
Nielsen, A. D., Arleth, L., & Westh, P. (2005). Biochimica et Biophysica Acta (BBA) – Proteins and. Proteomics, 1752, 124–132.
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Patel, R., Kumari, M. & Khan, A.B. Recent Advances in the Applications of Ionic Liquids in Protein Stability and Activity: A Review. Appl Biochem Biotechnol 172, 3701–3720 (2014). https://doi.org/10.1007/s12010-014-0813-6
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DOI: https://doi.org/10.1007/s12010-014-0813-6