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The role of parenteral nutrition

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Abstract

Patients with acute leukemia who undergo hematopoietic stem cell transplantation (HSCT) are susceptible to malnutrition caused by several factors including intensive cytotoxic therapy. This paper discusses the significance of malnutrition in these patients and provides an overview of nutrition therapy by the oral, enteral, and parenteral routes. The goal is to investigate whether the use of parenteral nutrition (PN) produces improved clinical outcomes in patients with acute leukemia and to identify criteria for the selection of patients most likely to benefit from this therapy. Although PN may be appropriate for patients suffering from complications such as graft-versus-host disease (GVHD) and mucositis, the data available at this time do not support PN as first-line therapy for all recipients of HSCT.

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  1. Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk R35, 44195, Cleveland, OH, USA

    Matt Kalaycio MD

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  1. Nicole B. Jacobson RD, LD, CNSD
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  2. Neha Parekh MS, RD, LD, CNSD
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  3. Matt Kalaycio MD
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Correspondence to Matt Kalaycio MD.

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Jacobson, N.B., Parekh, N. & Kalaycio, M. The role of parenteral nutrition. Curr Hematol Malig Rep 1, 188–194 (2006). https://doi.org/10.1007/s11899-996-0007-6

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