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Incidence and Prevalence of Atrial Fibrillation in Latinos: What’s New Since the Study in Latinos (SOL)?

  • Diversity and Health Equity in Cardiology (AE Johnson, Section Editor)
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Abstract

Purpose of Review

To assess contemporary epidemiological trends in AF incidence and prevalence in the LatinX population after the Hispanic Community Health Study/Study of Latinos.

Recent Findings

Atrial fibrillation (AF) remains the most abnormal heart rhythm condition globally and disproportionately impacts morbidity and mortality of communities that have been historically disadvantaged. The incidence and prevalence of AF is lower in the LatinX population compared to White individuals despite a higher burden of classic risk factors associated with AF. Since the Hispanic Community Health Study/Study of Latinos study on AF, recent data continues to demonstrate a similar lower burden of AF in the LatinX population compared to White individuals. However, the rates of incident AF may be accelerating faster in the LatinX population compared to their White counterparts. Furthermore, studies have found environmental and genetic risk factors that are associated with the development of AF within LatinX individuals, which may help explain the rising development of AF among the LatinX community. Recent research continues to show that LatinX populations are less likely to be treated with stroke reduction and rhythm control strategies and have a disproportionately higher burden of poor outcomes associated with AF compared to White patients.

Summary

Our review illuminates that further inclusion of LatinX individuals in AF randomized control trials and observational studies is imperative to understand the incidence and prevalence of AF in the LatinX community and improve overall morbidity and mortality.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Schnabel RB et al. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. The Lancet. 2015;386(9989):154–62.

    Article  Google Scholar 

  2. Go AS et al. Prevalence of diagnosed atrial fibrillation in adults national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors In Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285(18):2370–5.

    Article  CAS  PubMed  Google Scholar 

  3. Heckbert SR et al. Differences by race/ethnicity in the prevalence of clinically detected and monitor-detected atrial fibrillation. Circ Arrhythm Electrophysiol. 2020;13(1):e007698.

  4. Rodriguez CJ et al. Atrial fibrillation incidence and risk factors in relation to race-ethnicity and the population attributable fraction of atrial fibrillation risk factors: the Multi-Ethnic Study of Atherosclerosis. Ann Epidemiol. 2015;25(2):71–6.

  5. Borzecki AM et al. Racial differences in the prevalence of atrial fibrillation among males. J Natl Med Assoc. 2008;100(2):237–45.

    PubMed  Google Scholar 

  6. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22(8):983–8.

    Article  CAS  PubMed  Google Scholar 

  7. Bureau, US Census. Hispanic Heritage Month. Census.Gov; 2022. www.census.gov/newsroom/facts-for-features/2022/hispanic-heritage-month.html. Accessed 20 Jun 2023.

  8. Sorlie PD et al. Design and implementation of the Hispanic Community Health Study/Study of Latinos. Ann Epidemiol. 2010;20(8):629–41.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Linares JD et al. Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: the Hispanic Community Health Study/Study of Latinos. Heart Rhythm. 2019;16(5):686–93.

    Article  PubMed  PubMed Central  Google Scholar 

  10. •• Alonso A et al. Epidemiology of atrial fibrillation in the All of Us Research Program. PLOS ONE. 2022;17(3):e0265498. This prospective cohort study found that in Hispanic participants recruited for the All of Us Research Program from 2017 to 2019, the prevalence of atrial fibrillation (AF) was 1.8% and the incidence of newly diagnosed AF was less than 5.9%. The findings of this study also noted that the rate of incident AF was higher in Hispanic participants compared to non-Hispanic White participants.

  11. Dewland TA et al. Incident atrial fibrillation among Asians Hispanics Blacks and Whites. Circulation. 2013;128(23):2470–7.

    Article  PubMed  Google Scholar 

  12. Essien UR et al. Disparities in anticoagulant therapy initiation for incident atrial fibrillation by race/ethnicity among patients in the Veterans Health Administration system. JAMA Netw Open. 2021;4(7):e2114234.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Tamirisa KP et al. Racial and ethnic differences in the management of atrial fibrillation. CJC Open. 2021;3 Suppl 12:137-148.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Cubillos L et al. Burden of disease from atrial fibrillation in adults from seven countries in Latin America. Int J Gen Med. 2014;7:441–8.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Lloyd-Jones DM et al. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation. 2004;110(9):1042–6.

    Article  PubMed  Google Scholar 

  16. Alonso A et al. Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J. 2009;158(1):111–7.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Osman M et al. Racial differences in the prevalence of diagnosed atrial fibrillation among hospitalized patients. Mayo Clin Proc. 2021;96(9):2495–7.

    Article  PubMed  Google Scholar 

  18. Reinhardt SW et al. National trends in the burden of atrial fibrillation during hospital admissions for heart failure. J Am Heart Assoc. 2021;10(11):e019412.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Laslett DB et al. Racial differences in the incidence of atrial fibrillation after cryptogenic stroke. Heart Rhythm. 2021;18(6):847–52.

    Article  PubMed  Google Scholar 

  20. Shulman E et al. Relative contribution of modifiable risk factors for incident atrial fibrillation in Hispanics, African Americans and non-Hispanic Whites. Int J Cardiol. 2019;275:89–94.

    Article  PubMed  Google Scholar 

  21. Chalazan B et al. Association of rare genetic variants and early-onset atrial fibrillation in ethnic minority individuals. JAMA Cardiol. 2021;6(7):811–9.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Gonzalez-Cordero AF et al. Insight on the genetics of atrial fibrillation in Puerto Rican Hispanics. Stroke Res Treat. 2021;8819896.

    PubMed  PubMed Central  Google Scholar 

  23. • Essien UR et al. Association of race and ethnicity with oral anticoagulation and associated outcomes in patients with atrial fibrillation: findings from the Get With The Guidelines-Atrial Fibrillation Registry. JAMA Cardiol. 2022;7(12):1207–17. This retrospective cohort study using data from the Get With The Guidelines-Atrial Fibrillation registry found that patients hospitalized with AF who identified as Hispanic were the least likely to be prescribed an oral anticoagulant on discharge compared to patients of other racial and ethnic groups and Hispanic patients had a higher stroke risk than White patients.

    Article  PubMed  Google Scholar 

  24. Chen LY et al. CHA2DS2-VASc score and stroke prediction in atrial fibrillation in Whites, Blacks, and Hispanics. Stroke. 2019;50(1):28–33.

    Article  CAS  PubMed  Google Scholar 

  25. Mentias A et al. Racial and sex disparities in anticoagulation after electrical cardioversion for atrial fibrillation and flutter. J Am Heart Assoc. 2021;10(17):e021674.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Eberly LA et al. Racial/ethnic and socioeconomic disparities in management of incident paroxysmal atrial fibrillation. JAMA Netw Open. 2021;4(2):e210247.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Khan MZ et al. Representation of women, older patients, ethnic, and racial minorities in trials of atrial fibrillation. Pacing Clin Electrophysiol. 2021;44(3):423–31.

    Article  PubMed  PubMed Central  Google Scholar 

  28. • Sarraju A, Maron DJ, Rodriguez F. Under-reporting and under-representation of racial/ethnic minorities in major atrial fibrillation clinical trials. JACC: Clin Electrophysiol. 2020;6(6):739–41. Findings of this study note that only six of the 34 global clinical trials that formed the 2019 American Heart Association/American College of Cardiology/Heart Rhythm Society guidelines for AF reported Hispanic participants and Hispanic participants made up only 5.6% of the total study population of the six clinical trials which reported Hispanic participants.

  29. Nunes JC et al. Underrepresentation of ethnic and racial minorities in atrial fibrillation clinical trials. Circulation: Arrhythmia and Electrophysiology. 2021;14(12):e010452.

  30. Velasco-Mondragon E et al. Hispanic health in the USA: a scoping review of the literature. Public Health Rev. 2016;37:31.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Hoyt H et al. Demographic profile of patients undergoing catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2011;22(9):994–8.

    Article  PubMed  Google Scholar 

  32. Bhave PD et al. Race- and sex-related differences in care for patients newly diagnosed with atrial fibrillation. Heart Rhythm. 2015;12(7):1406–12.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Tamariz L et al. Racial disparities in the use of catheter ablation for atrial fibrillation and flutter. Clin Cardiol. 2014;37(12):733–7.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Golwala H et al. Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry. Am Heart J. 2016;174:29–36.

    Article  PubMed  Google Scholar 

  35. Kapoor A et al. Disparities in anticoagulation use by race and ethnicity in long-term care residents with atrial fibrillation. J Am Heart Assoc. 2021;10(23):e023428.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Essien UR et al. Race/ethnicity and sex-related differences in direct oral anticoagulant initiation in newly diagnosed atrial fibrillation: a retrospective study of Medicare data. J Natl Med Assoc. 2020;112(1):103–8.

    PubMed  Google Scholar 

  37. Kabra R et al. Effect of race on outcomes (stroke and death) in patients >65 years with atrial fibrillation. Am J Cardiol. 2015;116(2):230–5.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Bush D et al. Atrial fibrillation among African Americans, Hispanics and Caucasians: clinical features and outcomes from the AFFIRM trial. J Natl Med Assoc. 2006;98(3):330–9.

    PubMed  PubMed Central  Google Scholar 

  39. Gomez SE et al. Racial, ethnic, and sex disparities in atrial fibrillation management: rate and rhythm control. J Interv Card Electrophysiol. 2022.

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Funding

Dr. Jackson has received research grants from the National Institute of Health, specifically the National Institute on Minority Health and Health Disparities, is currently supported by 1K01HL159041 from the National Heart, Lung and Blood Institute and the American Heart Association under award number 851386.

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Correspondence to Larry R. Jackson.

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Conflict of Interest

Dr. Jackson serves as a consultant to Biosense Webster Inc., Johnson and Johnson, Sanofi, Bristol Myers Squibb, and Pfizer; and receives honoraria from Zoll LifeVest, CME Outfitters, Health Monitor, PRIME Education, and WebMD/Medscape. Dr. Khedagi and Dr. Ugowe have no relevant financial and non-financial interests to disclose.

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Khedagi, A., Ugowe, F. & Jackson, L.R. Incidence and Prevalence of Atrial Fibrillation in Latinos: What’s New Since the Study in Latinos (SOL)?. Curr Cardiol Rep 25, 901–906 (2023). https://doi.org/10.1007/s11886-023-01910-w

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