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Risk factors of acute cerebral infarction in patients with primary hypertension

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Abstract

Objective

To explore the risk factors of acute cerebral infarction (ACI) in patients with primary hypertension.

Methods

Patients diagnosed with primary hypertension and ACI and confirmed by MRI, who were admitted to Honghuagang District people’s Hospital, Zunyi City, from January 2020 to December 2020, were selected. Concurrent patients with primary hypertension were selected as the control group. The risk factor including sex, age, smoking, drinking, laboratory examination, and other complications was analyzed.

Results

Three hundred patients with hypertensive ACI and 117 cases with hypertension were included. The laboratory examination comparison between the two groups showed that patients in the ACI group had higher glycosylated hemoglobin, D-dimer and FDPs then patients of the control group (P < 0.05). There was significant association between diabetes mellitus and acute cerebral infarction in patients with primary hypertension (OR = 1.452, P = 0.004).

Conclusion

Poor control of blood glucose in pre-morbid diabetes mellitus may be related to the occurrence of ACI. Diabetes mellitus is an independent risk factor in ACI patients with primary hypertension.

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Availability of data and material

The datasets used or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

Zunyi Science and Technology Cooperation，No:HZ(2019)236.

Author information

Authors and Affiliations

  1. Department of Laboratory, People’s Hospital of Honghuagang District, 134 Linjiapo Road, Zunyi City, 563000, Guizhou Province, China

    Deliang Zheng, Xinmiao Li & Yongping Fu

Authors
  1. Deliang Zheng
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  2. Xinmiao Li
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  3. Yongping Fu
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Contributions

Guarantor of integrity of the entire study: Zheng Deliang, study concepts: Li Xinmiao, study design: Li Xinmiao, definition of intellectual content: Zheng Deliang, literature research: Li Xinmiao, clinical studies: Li Xinmiao, experimental studies: Li Xinmiao, data acquisition: Li Xinmiao, data analysis: Li Xinmiao, statistical analysis: Li Xinmiao, manuscript preparation: Li Xinmiao, manuscript editing: Li Xinmiao, Zheng Deliang, Fu Yongping, and manuscript review: Li Xinmiao, Zheng Deliang, Fu Yongping.

Corresponding author

Correspondence to Deliang Zheng.

Ethics declarations

Ethics approval and consent to participate

This study has been approved by the ethics committee of Honghuagang District people’s hospital. The study was performed in accordance with the 1964 Helsinki declaration on ethical standards. All participants and their families have agreed to use the information required for this study for scientific research and signed informed consent.

Consent for publication

Informed consent was obtained from all individual participants included in the study.

Conflict of interest

The authors declare no competing of interests.

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Cite this article

Zheng, D., Li, X. & Fu, Y. Risk factors of acute cerebral infarction in patients with primary hypertension. Ir J Med Sci 192, 2441–2445 (2023). https://doi.org/10.1007/s11845-022-03206-4

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  • DOI: https://doi.org/10.1007/s11845-022-03206-4

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