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Facile conversion of alcohols to olefins by tosylation and subsequent SiO2-promoted β-elimination

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Abstract

A convenient and effective procedure was developed for the conversion of alcohol to olefin by tosylation and subsequent β-elimination promoted by silica gel in this study. Treatment of the alcohols with p-toluenesulfonyl chloride in pyridine at 0°C affords tosylates which undergo β-elimination with silica gel in dichloromethane or chloroform at room temperature, yielding olefins with high productivity.

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Authors and Affiliations

  1. Key Laboratory of Marine Drugs of the Ministry of Education of China, School of Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China

    Ruan Xiaohong, Song Gaopeng, Zhang Yichun & Li Yingxia

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  1. Ruan Xiaohong
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  2. Song Gaopeng
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  3. Zhang Yichun
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  4. Li Yingxia
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Correspondence to Li Yingxia.

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Ruan, X., Song, G., Zhang, Y. et al. Facile conversion of alcohols to olefins by tosylation and subsequent SiO2-promoted β-elimination. J Ocean Univ. China 6, 196–198 (2007). https://doi.org/10.1007/s11802-007-0196-1

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  • DOI: https://doi.org/10.1007/s11802-007-0196-1

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