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Optimizing light delivery in scanning photoacoustic imaging for prostate

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Abstract

The purpose of this study was to optimize the light delivery method in a prostate photoacoustic imaging system. A three dimensional (3D) optical model of the human prostate was developed, and the optical energy distribution in the prostate was estimated via three-dimensional Monte Carlo simulation. Then, the feasibility of prostate photoacoustic imaging (PAI) using two endoscopic light delivery methods was studied. Photoacoustic pressure generation and the corresponding photoacoustic images had been obtained and the comparisons were made between each other. Also, the results of cylinder diffusing light source with different lengths were compared. After that, phantom experiment was carried out to validate the simulation results. Our results would be significant in the optimizing photoacoustic imaging system for an accurate diagnosis of prostate cancer.

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Authors and Affiliations

  1. School of Science, Jimei University, Xiamen, 361021, China

    Dong-qing Peng  (彭东青), Zhi-gao Liu  (刘志高) & Hui-zhen Xu  (徐惠真)

  2. Key Laboratory of Optoelectronic Science and Technology for Medicine (Ministry of Education of China), Fujian Provincial Key Laboratory of Photonic Technology, College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou, 350007, China

    Li-li Zhu  (朱莉莉) & Hui Li  (李晖)

Authors
  1. Dong-qing Peng  (彭东青)
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  2. Zhi-gao Liu  (刘志高)
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  3. Hui-zhen Xu  (徐惠真)
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  4. Li-li Zhu  (朱莉莉)
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  5. Hui Li  (李晖)
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Corresponding author

Correspondence to Hui Li  (李晖).

Additional information

This work has been supported by the National Natural Science Foundation of China (No.61675043), the Natural Science Foundation of Fujian Province (No.2018J01416), the Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education (No.JYG1808), and the National Fund Cultivation Plan of Jimei University (No.ZP2020059).

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Peng, Dq., Liu, Zg., Xu, Hz. et al. Optimizing light delivery in scanning photoacoustic imaging for prostate. Optoelectron. Lett. 17, 53–58 (2021). https://doi.org/10.1007/s11801-021-0077-7

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  • DOI: https://doi.org/10.1007/s11801-021-0077-7

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