Abstract
A man diagnosed with immunoglobulin G4 (IgG4)-related disease at the age of 65 years underwent abdominal aortic replacement due to an abdominal aortic aneurysm. In the same hospitalization period, a small coronary artery aneurysm was noticed. He was treated with corticosteroids and his serum IgG levels returned to normal. After experiencing sudden chest pain at age 74 years, coronary angiography showed that the size of the aneurysm had increased dramatically. He underwent coronary artery bypass graft and coronary artery resection without using cardiopulmonary bypass. Thus, we conclude that observation of aneurysms in patients with IgG4-related disease is important, even under corticosteroid therapy.
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Hamano H, Kawa S, Horiuchi A, Unno H, Furuya N, Akamatsu T, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med. 2001;344(10):732–8.
Tajima M, Nagai R, Hiroi Y. IgG4-related cardiovascular disorders. Int Heart J. 2014;55(4):287–95.
Kasashima S, Zen Y. IgG4-related inflammatory abdominal aortic aneurysm. Curr Opin Rheumatol. 2011;23(1):18–23.
Kan-o M, Kado Y, Sadanaga A, Tamiya S, Toyoshima S, Sakamoto M. Immunoglobulin G4-related multiple cardiovascular lesions successfully treated with a combination of open surgery and corticosteroid therapy. J Vasc Surg. 2015;61(6):1599–603.
Qian Q, Kashani KB, Miller DV. Ruptured abdominal aortic aneurysm related to IgG4 periaortitis. N Engl J Med. 2009;361(11):1121–3.
Ikutomi M, Matsumura T, Iwata H, Nishimura G, Ishizaki N, Hirata Y, et al. Giant tumorous lesions (correction of legions) surrounding the right coronary artery associated with immunoglobulin-G4-related systemic disease. Cardiology. 2011;120(1):22–6.
Patel NR, Anzalone ML, Buja LM, Elghetany MT. Sudden cardiac death due to coronary artery involvement by IgG4-related disease: a rare, serious complication of a rare disease. Arch Pathol Lab Med. 2014;138(6):833–6.
Keyser A, Hilker MK, Husser O, et al. Giant coronary aneurysms exceeding 5 cm in size. Interact Cardiovasc Thorac Surg. 2012;15(1):33–6.
Shanmugam V, Psaltis PJ, Wong DTL, et al. Outcomes after primary percutaneous coronary intervention for ST-elevation myocardial infarction caused by ectatic infarct related arteries. Heart Lung Circ. 2017;26(10):1059–68.
Yip HK, Chen MC, Hang CL, et al. Clinical features and outcome of coronary artery aneurysm in patients with acute myocardial infarction undergoing a primary percutaneous coronary intervention. Cardiology. 2002;98:132–40.
Kawasara A, Gil IJ, Alqahtani F, et al. Management of coronary artery aneurysms. JACC Cardiovasc Interv. 2018;11(13):1211–23.
Kim TH, Marfatia R, Lee J, Azrin M. Giant coronary aneurysm management with Viabahn covered stent. Cardiovasc Revasc Med. 2017;18(6):56–9.
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Matsuyama, S., Kishigami, T. & Sakamoto, M. A case of giant right coronary artery aneurysm due to IgG4-related disease. Gen Thorac Cardiovasc Surg 68, 1453–1456 (2020). https://doi.org/10.1007/s11748-019-01272-7
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DOI: https://doi.org/10.1007/s11748-019-01272-7