Abstract
Fe3O4/CeO2/C-dot nanozyme as a hybrid nanocomposite was prepared and characterized. Fe3O4/CeO2/C-dot nanocomposite presents horseradish peroxidase-like catalytic activity due to the presence of triple nanozymes in the nanocomposite. The kinetic parameters of nanozymatic assay present Michaelis–Menten behavior. A colorimetric assay for determination of H2O2 was introduced based on the catalytic activity of Fe3O4/CeO2/C-dot nanocomposite in H2O2/TMB system. In the presence of nanozyme, H2O2 reduction occurs and TMB was oxidized to ox-TMB which causes a blue color in the system. In this manner, intensity of the blue color is dependent on H2O2 concentration. Also, Fe3O4/CeO2/C-dot nanocomposite exhibits electrocatalytic activity toward H2O2 reduction. Multi-walled carbon nanotube/ionic liquid paste (MWIL) electrode was modified by Fe3O4/CeO2/C-dot nanocomposite which reveals higher electrocatalytic activity toward hydrogen peroxide rather than Fe3O4/CeO2 and Fe3O4/C-dot-modified electrodes. Catalytic and electrocatalytic determination of hydrogen peroxide shows the linear ranges of 1.0 × 10–6–5.0 × 10–13 M and 2.0 × 10–8 to 1.0 × 10–6 M, respectively.
Graphic abstract
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abo-Hamad A, Alsaadi MA, Hayyan M, Juneidi I, Hashim MA (2016) Ionic liquid-carbon nanomaterial hybrids for electrochemical sensor applications: a review. Electrochim Acta 193:321–343
Ali A, Ahmed S (2018) A review on chitosan and its nanocomposites in drug delivery. Int J Biol Macromol 109:273–286. https://doi.org/10.1016/j.ijbiomac.2017.12.078
Ali S, Abbas F, Qayyum MF, Zia-ur-Rehman M, Rizwan M, Farid M, Adrees M, Ok YS, Ibrahim M (2016) Effect of metal and metal oxide nanoparticles on growth and physiology of globally important food crops: a critical review. J Hazard Mater 322:2–16
Babitha KK, Sreedevi A, Priyanka KP, Sabu B, Varghese T (2015) Structural characterization and optical studies of CeO2 nanoparticles synthesized by chemical precipitation. Indian J Pure Appl Phys 53:596–603
Baldim V, Bedioui F, Mignet N, Margaill I, Berret JF (2018) The enzyme-like catalytic activity of cerium oxide nanoparticles and its dependency on Ce 3+ surface area concentration. Nanoscale 10:6971–6980. https://doi.org/10.1039/c8nr00325d
Bhateria R, Singh R (2019) A review on nanotechnological application of magnetic iron oxides for heavy metal removal. J Water Process Eng 31:100845. https://doi.org/10.1016/j.jwpe.2019.100845
Charbgoo F, Bin AM, Darroudi M (2017) Cerium oxide nanoparticles: green synthesis and biological applications. Int J Nanomedicine 12:1401–1413
Dutta AK, Maji SK, Srivastava DN, Mondal A, Biswas P, Paul P, Adhikary B (2012) Synthesis of FeS and FeSe nanoparticles from a single source precursor: a study of their photocatalytic activity, peroxidase-like behavior, and electrochemical sensing of H 2O 2. ACS Appl Mater Interfaces 4:1919–1927. https://doi.org/10.1021/am300408r
Espinosa A, Di Corato R, Kolosnjaj-Tabi J, Flaud P, Pellegrino T, Wilhelm C (2016) Duality of iron oxide nanoparticles in cancer therapy: amplification of heating efficiency by magnetic hyperthermia and photothermal bimodal treatment. ACS Nano 10:2436–2446. https://doi.org/10.1021/acsnano.5b07249
Gao L, Zhuang J, Nie L, Zhang J, Zhang Y, Gu N, Wang T, Feng J, Yang D, Perrett S, Yan X (2007) Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol 2:577–583. https://doi.org/10.1038/nnano.2007.260
Gawande MB, Bonifácio VDB, Varma RS, Nogueira ID, Bundaleski N, Ghumman CAA, Teodoro OMND, Branco PS (2013) Magnetically recyclable magnetite-ceria (Nanocat-Fe-Ce) nanocatalyst-applications in multicomponent reactions under benign conditions. Green Chem 15:1226–1231. https://doi.org/10.1039/c3gc40375k
Golchin J, Golchin K, Alidadian N, Ghaderi S, Eslamkhah S, Eslamkhah M, Akbarzadeh A (2017) Nanozyme applications in biology and medicine: an overview. Artif Cells, Nanomed Biotechnol 45:1069–1076. https://doi.org/10.1080/21691401.2017.1313268
Honarasa F, Kamshoori FH, Fathi S, Motamedifar Z (2019) Carbon dots on V2O5 nanowires are a viable peroxidase mimic for colorimetric determination of hydrogen peroxide and glucose. Microchim Acta 186:234. https://doi.org/10.1007/s00604-019-3344-6
Honarasa F, Peyravi F, Amirian H (2019) C-dots/Mn3O4 nanocomposite as an oxidase nanozyme for colorimetric determination of ferrous ion. J Iran Chem Soc. https://doi.org/10.1007/s13738-019-01787-z
Honarasa F, Zare M, Yousefinejad S (2016) Comparison of different carbon nanostructures influence on potentiometric performance of carbon paste electrode. Russ J Electrochem 52:955–959. https://doi.org/10.1134/S1023193516100050
Huang F, Wang J, Chen W, Wan Y, Wang X, Cai N, Liu J, Yu F (2018) Synergistic peroxidase-like activity of CeO2-coated hollow Fe3O4 nanocomposites as an enzymatic mimic for low detection limit of glucose. J Taiwan Inst Chem Eng 83:40–49. https://doi.org/10.1016/j.jtice.2017.12.011
Iqbal A, Iqbal K, Li B, Gong D, Qin W (2017) recent advances in iron nanoparticles: preparation, properties, biological and environmental application. J Nanosci Nanotechnol 17:4386–4409. https://doi.org/10.1166/jnn.2017.14196
Jiao X, Song H, Zhao H, Bai W, Zhang L, Lv Y (2012) Well-redispersed ceria nanoparticles: promising peroxidase mimetics for H 2O 2 and glucose detection. Anal Methods 4:3261–3267. https://doi.org/10.1039/c2ay25511a
Jin S, Wu C, Ye Z, Ying Y (2019) Designed inorganic nanomaterials for intrinsic peroxidase mimics: a review. Sens Actuators B Chem 283:18–34
Kang T, Kim YG, Kim D, Hyeon T (2020) Inorganic nanoparticles with enzyme-mimetic activities for biomedical applications. Coord Chem Rev 403:213092. https://doi.org/10.1016/j.ccr.2019.213092
Li B, Chen D, Nie M, Wang J, Li Y, Yang Y (2018) Carbon dots/Cu2O composite with intrinsic high protease-like activity for hydrolysis of proteins under physiological conditions. Part Part Syst Charact 35:1800277. https://doi.org/10.1002/ppsc.201800277
Liao H, Liu Y, Chen M, Wang M, Yuan H, Hu L (2019) A colorimetric heparin assay based on the inhibition of the oxidase mimicking activity of cerium oxide nanoparticles. Acta Microchim. https://doi.org/10.1007/s00604-019-3382-0
Liu H, Ye T, Mao C (2007) Fluorescent carbon nanoparticles derived from candle soot. Angew Chemie Int Ed 46:6473–6475. https://doi.org/10.1002/anie.200701271
Lv Y, Ma M, Huang Y, Xia Y (2018) Carbon dot nanozymes: how to be close to natural enzymes. Chem Eur J. https://doi.org/10.1002/chem.201804419
Ma M, Xie J, Zhang Y, Chen Z, Gu N (2013) Fe3O4@Pt nanoparticles with enhanced peroxidase-like catalytic activity. Mater Lett 105:36–39. https://doi.org/10.1016/j.matlet.2013.04.020
Masoudi A, Honarasa F (2018) C-dots/Fe3O4 magnetic nanocomposite as nanoadsorbent for removal of heavy metal cations. J Iran Chem Soc 15:1199–1205. https://doi.org/10.1007/s13738-018-1318-y
Montini T, Melchionna M, Monai M, Fornasiero P (2016) Fundamentals and catalytic applications of CeO2-based materials. Chem Rev 116:5987–6041. https://doi.org/10.1021/acs.chemrev.5b00603
Nikaeen G, Abbaszadeh S, Yousefinejad S (2020) Application of nanomaterials in treatment, anti-infection and detection of coronaviruses. Nanomedicine (Lond) 15:1501–1512
Peng Z, Liu X, Zhang W, Zeng Z, Liu Z, Zhang C, Liu Y, Shao B, Liang Q, Tang W, Yuan X (2020) Advances in the application, toxicity and degradation of carbon nanomaterials in environment: a review. Environ Int 134:105298
Rathore B, Sunwoo K, Jangili P, Kim J, Kim JH, Huang M, Xiong J, Sharma A, Yang Z, Qu J, Kim JS (2019) Nanomaterial designing strategies related to cell lysosome and their biomedical applications: a review. Biomaterials 211:25–47
Rezaee E, Honarasa F (2018) Determination of tryptophan by using of activated multi-walled carbon nanotube ionic liquid electrode. Russ J Electrochem 54:1073–1080. https://doi.org/10.1134/S102319351812008X
Sadravi S, Honarasa F (2019) Spectrophotometric nanomolar determination of glucose by using C-dots/ Fe3O4 magnetic nanozyme. J Chem Sci 131:1–7. https://doi.org/10.1007/s12039-019-1629-2
Sharma RK, Dutta S, Sharma S, Zboril R, Varma RS, Gawande MB (2016) Fe 3 O 4 (iron oxide)-supported nanocatalysts: synthesis, characterization and applications in coupling reactions. Green Chem 18:3184–3209. https://doi.org/10.1039/c6gc00864j
Shelkar RS, Balsane KE, Nagarkar JM (2015) Magnetically separable nano CeO2: a highly efficient catalyst for ligand free direct C-H arylation of heterocycles. Tetrahedron Lett 56:693–699
Shi W, Wang Q, Long Y, Cheng Z, Chen S, Zheng H, Huang Y (2011) Carbon nanodots as peroxidase mimetics and their applications to glucose detection. Chem Commun 47:6695. https://doi.org/10.1039/c1cc11943e
Su L, Cai Y, Wang L, Dong W, Mao G, Li Y, Zhao M, Ma Y, Zhang H (2020) Hemin@carbon dot hybrid nanozymes with peroxidase mimicking properties for dual (colorimetric and fluorometric) sensing of hydrogen peroxide, glucose and xanthine. Microchim Acta 187:132. https://doi.org/10.1007/s00604-019-4103-4
Sun H, Zhou Y, Ren J, Qu X (2018) Carbon nanozymes: enzymatic properties, catalytic mechanism, and applications. Angew Chem Int Ed 57:9224–9237. https://doi.org/10.1002/anie.201712469
Wang H, Li S, Si Y, Sun Z, Li S, Lin Y (2014) Recyclable enzyme mimic of cubic Fe3O4 nanoparticles loaded on graphene oxide-dispersed carbon nanotubes with enhanced peroxidase-like catalysis and electrocatalysis. J Mater Chem B 2:4442–4448. https://doi.org/10.1039/C4TB00541D
Wang Q, Wei H, Zhang Z, Wang E, Dong S (2018) Nanozyme: an emerging alternative to natural enzyme for biosensing and immunoassay. TrAC Trends Anal Chem 105:218–224. https://doi.org/10.1016/j.trac.2018.05.012
Wang Y, Liang M, Wei T (2020) Types of nanozymes: materials and activities. In: Yan X (ed) Nanozymology: nanostructure science and technology. Springer, Singapore, pp 41–77
Wei H, Wang E (2013) Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes. Chem Soc Rev 42:6060–6093
Wei H, Wang E (2008) Fe3O4 magnetic nanoparticles as peroxidase mimetics and their applications in H2O2 and glucose detection. Anal Chem 80:2250–2254. https://doi.org/10.1021/ac702203f
Wu J, Wang X, Wang Q, Lou Z, Li S, Zhu Y, Qin L, Wei H (2019) Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II). Chem Soc Rev 48:1004–1076. https://doi.org/10.1039/c8cs00457a
Yao X, Liu T, Xie Y, Chu Z, Jin W (2020) In situ-forming magnetic Fe3O4 nanoroses on defect-controllable mesoporous graphene oxide for enzyme-mimic sensing. Ind Eng Chem Res 59:17934–17943. https://doi.org/10.1021/acs.iecr.0c03706
Yee MJ, Mubarak NM, Abdullah EC, Khalid M, Walvekar R, Karri RR, Nizamuddin S, Numan A (2019) Carbon nanomaterials based films for strain sensing application—a review. Nano-Struct Nano-Objects. https://doi.org/10.1016/j.nanoso.2019.100312
Yousefinejad S, Rasti H, Hajebi M, Kowsari M, Sadravi S, Honarasa F (2017) Design of C-dots/Fe3O4 magnetic nanocomposite as an efficient new nanozyme and its application for determination of H2O2 in nanomolar level. Sens Actuators B Chem 247:691–696. https://doi.org/10.1016/j.snb.2017.02.145
Zhang Z, Zhu H, Wang X, Yang X (2011) Sensitive electrochemical sensor for hydrogen peroxide using Fe3O4 magnetic nanoparticles as a mimic for peroxidase. Microchim Acta 174:183–189. https://doi.org/10.1007/s00604-011-0600-9
Zhang M, Bai L, Shang W, Xie W, Ma H, Fu Y, Fang D, Sun H, Fan L, Han M, Liu C, Yang S (2012) Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells. J Mater Chem 22:7461–7467. https://doi.org/10.1039/c2jm16835a
Zhao H, Dong Y, Jiang P, Wang G, Zhang J (2015) Highly dispersed CeO2 on TiO2 nanotube: a synergistic nanocomposite with superior peroxidase-like activity. ACS Appl Mater Interfaces 7:6451–6461. https://doi.org/10.1021/acsami.5b00023
Zhang L, Hai X, Xia C, Chen XW, Wang JH (2017) Growth of CuO nanoneedles on graphene quantum dots as peroxidase mimics for sensitive colorimetric detection of hydrogen peroxide and glucose. Sens Actuators, B Chem 248:374–384. https://doi.org/10.1016/j.snb.2017.04.011
Zhang Y, Jin Y, Cui H, Yan X, Fan K (2020) Nanozyme-based catalytic theranostics. RSC Adv 10:10–20. https://doi.org/10.1039/C9RA09021E
Zhu J, Nie W, Wang Q, Li J, Li H, Wen W, Bao T, Xiong H, Zhang X, Wang S (2018) In situ growth of copper oxide-graphite carbon nitride nanocomposites with peroxidase-mimicking activity for electrocatalytic and colorimetric detection of hydrogen peroxide. Carbon N Y 129:29–37
Zuo X, Peng C, Huang Q, Song S, Wang L, Li D, Fan C (2009) Design of a carbon nanotube/magnetic nanoparticle-based peroxidase-like nanocomplex and its application for highly efficient catalytic oxidation of phenols. Nano Res 2:617–623. https://doi.org/10.1007/s12274-009-9062-3
Acknowledgements
The authors acknowledge the support to this study by Islamic Azad University, Shiraz Branch.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
On behalf of all authors, the corresponding author states that there is no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Honarasa, F., Keshtkar, S., Eskandari, N. et al. Catalytic and electrocatalytic activities of Fe3O4/CeO2/C-dot nanocomposite. Chem. Pap. 75, 2371–2378 (2021). https://doi.org/10.1007/s11696-020-01443-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11696-020-01443-4