Abstract
Obesity is a rising medical condition; metabolic and bariatric surgery, mainly sleeve gastrectomy, offers a successful weight loss option which is maintainable. Weight loss is heavily dependent on energy expenditure. Resting energy expenditure (REE) after sleeve gastrectomy has been described in the literature with varying results. In this review, we review all published literature that described REE post sleeve gastrectomy in human. We found that REE goes down after sleeve gastrectomy as the weight loss occurs and REE when adjusted for weight (REE/kg) only goes up significantly in the 2 studies that included youths. REE/kg did not significantly change in studies including adults ages 30 and above. This study is the first that reviews and summarized REE findings post sleeve gastrectomy and more studies are needed especially targeting the pediatric and youth populations.
References
Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of obesity and severe obesity among adults: United States, 2017–2018. NCHS Data Brief. 2020;360:1–8.
Ogden CL, Fryar CD, Martin CB, et al. Trends in obesity prevalence by race and Hispanic origin-1999-2000 to 2017–2018. JAMA. 2020;324(12):1208–10.
Armstrong SC, Bolling CF, Michalsky MP, Reichard KW. Pediatric metabolic and bariatric surgery: evidence, barriers, and best practices. Pediatrics. 2019;144(6).
Ye Y, Abu El Haija M, Morgan DA, et al. Endocannabinoid receptor-1 and sympathetic nervous system mediate the beneficial metabolic effects of gastric bypass. Cell Rep. 2020;33(4):108270.
Golzarand M, Toolabi K, Hedayati M, Azam K, Douraghi M, Djafarian K. Comparative study of resting metabolic rate and plasma amino acid profile in patients who underwent laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: 6-month follow-up study. Obes Surg. 2019;29(10):3125–32.
Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332(10):621–8.
Zechner JF, Mirshahi UL, Satapati S, et al. Weight-independent effects of roux-en-Y gastric bypass on glucose homeostasis via melanocortin-4 receptors in mice and humans. Gastroenterology. 2013;144(3):580-590.e587.
Schneider J, Peterli R, Gass M, Slawik M, Peters T, Wölnerhanssen BK. Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass lead to equal changes in body composition and energy metabolism 17 months postoperatively: a prospective randomized trial. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 2016;12(3):563–70.
Harris DA, Mina A, Cabarkapa D, et al. Sleeve gastrectomy enhances glucose utilization and remodels adipose tissue independent of weight loss. Am J Physiol Endocrinol Metab. 2020;318(5):E678-e688.
Rickard FA, Torre Flores LP, Malhotra S, et al. Comparison of measured and estimated resting energy expenditure in adolescents and young adults with severe obesity before and 1 year after sleeve gastrectomy. Front Pediatr. 2019;7:37.
Brehm B, Summer S, Jenkins T, D’Alessio D, Inge T. Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 2020;16(5):599–606.
Bettini S, Bordigato E, Fabris R, et al. Modifications of resting energy expenditure after sleeve gastrectomy. Obes Surg. 2018;28(8):2481–6.
Chu L, Steinberg A, Mehta M, et al. Resting energy expenditure and metabolic adaptation in adolescents at 12 months after bariatric surgery. J Clin Endocrinol Metab. 2019;104(7):2648–56.
Schiavo L, Scalera G, Pilone V, De Sena G, Iannelli A, Barbarisi A. Fat mass, fat-free mass, and resting metabolic rate in weight-stable sleeve gastrectomy patients compared with weight-stable nonoperated patients. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 2017;13(10):1692–9.
Acknowledgements
We would like to acknowledge Stanford Lane Library Staff Connie Wong for help with the literature search.
We would like to thank the Stanford Quantitative Sciences Unit (QSU) for the statistical consultation (Maya Mathur).
Author information
Authors and Affiliations
Contributions
MA summarized the literature search, personally reviewed all papers which resulted from search, consulted with statisticians at Stanford University, emailed authors from papers included to obtain missing data, and wrote the paper.
RK gave overall mentorship and review on performing literature search, inclusion/exclusion criteria on papers, and data extraction, and reviewed and edited the manuscript.
Corresponding author
Ethics declarations
Research involving human and animal rights
This article does not contain any studies with human participants or animals performed by any of the authors.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Key points
- This is a review of resting energy expenditure (REE) after sleeve gastrectomy (SG).
- REE goes down after SG as weight loss occurs.
- REE per kg (REE/kg) is a better estimate since REE is dependent on weight.
- REE/kg does not change significantly in studies involving adult participants.
- REE/kg shows significant increase after SG only in studies involving young adults.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Abu El Haija, M., Kohli, R. Changes in Resting Energy Expenditure After Sleeve Gastrectomy: a Review of the Literature. OBES SURG 32, 2484–2487 (2022). https://doi.org/10.1007/s11695-022-06092-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-022-06092-y