Abstract
Background
Preliminary data suggest that patients with actively treated depression should expect the same outcomes after surgery. The objective of this study was to compare weight loss 12 months after gastric bypass surgery in patients taking antidepressants before surgery (AD) versus those who were not (non-AD).
Methods
IRB approval was obtained. All patients gave informed consent prior to participating in the study. Medication and weight loss histories were retrospectively reviewed in adult patients who were followed at 12 months post-surgery.
Results
145 of 364 patients were taking antidepressants at baseline. There was no significant difference in weight loss between the AD and non-AD groups at 12 months (p > 0.05).
Conclusions
Taking antidepressant medication prior to gastric bypass surgery did not affect weight loss outcomes at 12 months.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
DeMaria EJ. Bariatric surgery for morbid obesity. N Engl J Med. 2007;356:2176–83.
Ma Y, Pagoto SL, Olendzki BC, et al. Predictors of weight status following laparoscopic gastric bypass. Obes Surg. 2006;16:1227–31.
Santry HP, Chin MN, Cagney KA, et al. The use of multidisciplinary teams to evaluate bariatric surgery patients: results from a national survey in the USA. Obes Surg. 2006;16:59–66.
Wadden TA, Sarwer DB. Behavioral assessment of candidates for bariatric surgery: a patient oriented approach. Obesity. 2006;14:53s–62.
van Hout GCM, Verschure SKM, van Heck GL. Psychosocial predictors of success following bariatric surgery. Obes Surg. 2995;15:552–60.
Wadden TA, Sarwer DB, Fabricatore AN, et al. Psychosocial and behavioral status of patients undergoing bariatric surgery: what to expect before and after surgery. Med Clin N Am. 2007;91:451–69.
Munoz DJ, Chen E, Fischer S, et al. Considerations for the use of the Beck depression inventory in the assessment of weight loss surgery seeking patients. Obes Surg. 2007;17:1097–101.
Averbuch Y, Heshka S, El-Shoreya H, et al. Depression score predicts weight loss following Roux-en-Y gastric bypass. Obes Surg. 2003;13:833–6.
Malone M, Alger SA. Binge status and quality of life after gastric bypass surgery: a 1 year study. Obes Res. 2004;12:473–81.
Alger-Mayer S, Rosati C, Polimeni J, et al. Pre-operative binge eating status and gastric bypass surgery: a long term outcome study. Obes Surg. 2009;19:139–45.
Love RJ, Love AS, Bower S, et al. Impact of antidepressant use on gastric bypass surgery patients' weight loss and health related quality of life outcomes. Psychosomatics. 2008;49:478–86.
Malone M, Alger-Mayer SA. Medication use patterns after gastric bypass surgery for weight management. Ann Pharmacother. 2005;39:637–42. doi:10.1345/aph.1E393.
Sears D, Fillmore G, Bui M, et al. Evaluation of gastric bypass patients 1 year after surgery: changes in quality of life and obesity related conditions. Obes Surg. 2008;18:1522–5.
Ashton DA, Favretti F, Segato G. Preoperative psychological testing another form of prejudice. Obes Surg. 2008;18:1330–7.
LeMont D, Moorehead MK, Parish MS, et al. Suggestions for the pre-surgical psychological assessment of bariatric surgery candidates. Pre-Surgical Psychological Guidelines Oct 2004; 1–29. American Society for Metabolic Bariatric Surgery at www.asbms.org accessed December 1st 2010
Conflict of interest
There was no funding support. There are no conflicts of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Malone, M., Alger-Mayer, S.A. & Polimeni, J.M. Antidepressant Drug Therapy Does Not Affect Weight Loss One Year after Gastric Bypass Surgery. OBES SURG 21, 1721–1723 (2011). https://doi.org/10.1007/s11695-010-0351-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-010-0351-4