References
Antoniou M, Habib M, Howard C, Jennings R, Leifert C, Nodari R, Robinson C, Fagan J (2012) Teratogenic effects of glyphosate-based herbicides: divergence of regulatory decisions from scientific evidence. J Environ Anal Toxicol S 4(006):2161–0525
Benbrook CM (2019) How did the US EPA and IARC reach diametrically opposed conclusions on the genotoxicity of glyphosate-based herbicides? Environ Sci Eur 31(1):2
Faniband MH, Noren E, Littorin M, Lindh CH (2021) Human experimental exposure to glyphosate and biomonitoring of young Swedish adults. Int J Hyg Environ Health 231:113657
Garattini S (1985) Toxic effects of chemicals: difficulties in extrapolating data from animals to man. Crit Rev Toxicol 16(1):1–29
Giri S, Bader A (2011) Improved preclinical safety assessment using micro-BAL devices: the potential impact on human discovery and drug attrition. Drug Discovery Today 16(9–10):382–397
Greek R, Pippus A, Hansen LA (2012) The Nuremberg Code subverts human health and safety by requiring animal modeling. BMC Med Ethics 13:16
IARC (2015) IARC monographs on the evaluation on carcinogenic risk on human. WHO Press, World Health Organization, p 112
Inserm (2021) Pesticides and health effects: new data. Collection Expertise collective. M. E. Sciences, INSERM
Krüger M, Schledorn P, Schrödl W, Hoppe HW, Lutz W, Shehata AA (2014) Detection of glyphosate residues in animals and humans. J Environ Anal Toxicol 4:5(2). https://doi.org/10.4172/2161-0525.1000230
Leon ME, Schinasi LH, Lebailly P, Beane Freeman LE, Nordby KC, Ferro G, Monnereau A, Brouwer M, Tual S, Baldi I, Kjaerheim K, Hofmann JN, Kristensen P, Koutros S, Straif K, Kromhout H, Schuz J (2019) Pesticide use and risk of non-Hodgkin lymphoid malignancies in agricultural cohorts from France, Norway and the USA: a pooled analysis from the AGRICOH consortium. Int J Epidemiol 48(5):1519–1535
Mesnage R, Defarge N, De Vendômois JS, Séralini G (2015) Potential toxic effects of glyphosate and its commercial formulations below regulatory limits. Food Chem Toxicol 84:133–153
Myers JP, Antoniou MN, Blumberg B, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vandenberg LN, Vom Saal FS, Welshons WV, Benbrook CM (2016) Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health 15:19
Niemann L, Sieke C, Pfeil R, Solecki R (2015) A critical review of glyphosate findings in human urine samples and comparison with the exposure of operators and consumers. J Verbr Lebensm 10(1):3–12
Solomon KR (2020) Estimated exposure to glyphosate in humans via environmental, occupational, and dietary pathways: an updated review of the scientific literature. Pest Manag Sci 76(9):2878–2885
Trasande L, Vandenberg LN, Bourguignon J-P, Myers JP, Slama R, Vom Saal F, Zoeller RT (2016) Peer-reviewed and unbiased research, rather than ‘sound science’, should be used to evaluate endocrine-disrupting chemicals. J Epidemiol Community Health 70(11):1051–1056
Vandenberg LN, Blumberg B, Antoniou MN, Benbrook CM, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP (2017) Is it time to reassess current safety standards for glyphosate-based herbicides? J Epidemiol Community Health 71(6):613–618
Vicini JL, Jensen PK, Young BM, Swarthout JT (2021) Residues of glyphosate in food and dietary exposure. Compr Rev Food Sci Food Saf 20(5):5226–5257
Zhang L, Rana I, Shaffer RM, Taioli E, Sheppard L (2019) Exposure to glyphosate-based herbicides and risk for non-Hodgkin lymphoma: a meta-analysis and supporting evidence. Mutat Res 781:186–206
Zoller O, Rhyn P, Zarn JA, Dudler V (2020) Urine glyphosate level as a quantitative biomarker of oral exposure. Int J Hyg Environ Health 228:113526
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Daniel Grau, Nicole Grau, and Quentin Gascuel are members of the Campagne Glyphosate Association.
Cécile Stratonovitch is a member of the board of directors of the association Alerte des médecins sur les pesticides, dedicated to providing information on the health effects of pesticides, on a non-profit basis.
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Grau, D., Grau, N., Gascuel, Q. et al. Answer to “Comments on ‘Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers’”. Environ Sci Pollut Res 29, 46377–46379 (2022). https://doi.org/10.1007/s11356-022-20862-2
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DOI: https://doi.org/10.1007/s11356-022-20862-2