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Impact of ambient fine particulate matter on emergency department admissions for circulatory system disease in a city in Northeast China

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Abstract

The cardiovascular impact of fine particles has caused great concern worldwide. However, evidences on the impact of fine particulate matter (PM2.5) on emergency department (ED) admissions for circulatory system disease in Northeast China is limited. We assessed the acute, lag, cumulative, and harvesting effects of PM2.5 on ED admissions for circulatory system diseases and their exposure-response relationship. A total of 26,168 ED admissions, including those for hypertension, ischemic heart disease (IHD), arrhythmia, heart failure (HF), and cerebrovascular events (CVE), were collected from the Shenyang Emergency Center from 1 January 2017 to 31 December 2018. The relationship between PM2.5 and ED admissions for circulatory system disease was estimated using a distributed lag non-linear model and a generalized additive quasi-Poisson model. We stratified the analyses by temperature. Air pollution was positively correlated with daily ED admissions for circulatory system disease or other cause-specific diseases under different lag structures. For every 10-μg/m3 increase in the PM2.5 concentration, the relative risk of daily ED admissions for circulatory system disease was 1.007 [95% confidence interval (CI), 1.001–1.013] in lag0, 1.007 (95%CI, 1.000–1.013) in lag1, and 1.011 (95%CI, 1.002–1.021) in lag03. A lag effect was found in IHD, a cumulative effect was found in CVE, and both lag and cumulative effects were found in hypertension and arrhythmia. A harvesting effect was observed in daily ED admissions for circulatory system disease and HF. We found no interaction between pollutants and temperature. We observed a monotonic and almost linear exposure-response relationship between PM2.5 and circulatory system disease with no threshold effect.PM2.5 contributes to obvious acute, lag, cumulative, and harvesting effects on circulatory system disease. PM2.5 was associated with the risk of daily ED admissions for circulatory system disease, hypertension, IHD, arrhythmia, HF, and CVE. Therefore, air quality management must be strengthened.

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The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Funding

This study was supported by the National Natural Science Foundations of China (42077396); Key Projects of Natural Science Foundation of Liaoning Province, China (20170541038). We appreciate the support of Key Laboratory of Environmental Health Damage Research and Assessment, Liaoning Province, for this research.

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  1. Chenkai Zhao and Qidian Li contributed equally to this work.

Authors and Affiliations

  1. Department of Environmental Health, School of Public Health, China Medical University, Key Laboratory of Environmental Health Damage Research and Assessment, Shenyang, 110122, Liaoning, China

    Chenkai Zhao & Qidian Li

  2. Liaoning Provincial Center for Disease Control and Prevention, Shenyang, 110000, Liaoning, China

    Zhongming Cui, JunLong Wang, Li Sun & Yan Yin

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Contributions

Chenkai Zhao: Conceptualization; Methodology; Software; Data curation; Writing, original draft. Qidian Li: Writing, original draft. Zhongming Cui: Writing, review and editing. Junlong Wang: Writing, review and editing. Junlong Wang: Writing, review and editing. Li Sun: Writing, review and editing. Yan Yin: Project administration; Conceptualization; Writing, review and editing.

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Correspondence to Yan Yin.

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Zhao, C., Li, Q., Cui, Z. et al. Impact of ambient fine particulate matter on emergency department admissions for circulatory system disease in a city in Northeast China. Environ Sci Pollut Res 28, 62839–62852 (2021). https://doi.org/10.1007/s11356-021-15222-5

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