Abstract
Natural arsenic contamination is a critical problem for various places around the world. Simav Plain (Kutahya, Turkey) is one such area that was shown to have natural arsenic contamination in its waters and soils. Arsenic exposure through ingestion of edible crops cultivated in Simav Plain and associated health risks were assessed in this study. To achieve this objective, arsenic levels in 18 crop species were estimated based on measured soil arsenic concentrations. Individual and aggregate non-carcinogenic and carcinogenic risks associated with ingestion of arsenic-contaminated crops were then assessed with scenario-based deterministic point estimates and stochastic population estimates. Monte Carlo simulation was used for the estimation of population health risks. Accordingly, wheat was found as the highest-ranked crop specie for the both types of health risks, followed by tomato and potato, which are three of the most consumed crops in the region. The risk levels estimated in this study were relatively high, indicating consumption of crops grown in the plain may be posing significant health risks even at lower-bound estimates. Consuming wheat, tomato, potato, and their products from uncontaminated sources was found to reduce the aggregate risks up to 88% implicating the importance of proposing suitable management measures for similar risk-prone areas.
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References
Ahmed MK, Shaheen N, Islam MS, Habibullah-Al-Mamun M, Islam S, Islam MM, Kundu GK, Bhattacharjee L (2016) A comprehensive assessment of arsenic in commonly consumed foodstuffs to evaluate the potential health risk in Bangladesh. Sci Total Environ 544:125–133. https://doi.org/10.1016/j.scitotenv.2015.11.133
Alam MO, Chakraborty S, Bhattacharya T (2016) Soil arsenic availability and transfer to food crops in Sahibganj, India with reference to human health risk. Environ Process 3:763–779. https://doi.org/10.1007/s40710-016-0184-9
Alexander PD, Alloway BJ, Dourado AM (2006) Genotypic variation in the accumulation of Cd, Cu, Pb and Zn exhibited by six commonly grown vegetables. Environ Pollut 144:736–745. https://doi.org/10.1016/j.envpol.2006.03.001
Antoniadis V, Shaheen SM, Boersch J, Frohne T, Du Laing G, Rinklebe J (2017) Bioavailability and risk assessment of potentially toxic elements in garden edible vegetables and soils around a highly contaminated former mining area in Germany. J Environ Manag 186:192–200. https://doi.org/10.1016/j.jenvman.2016.04.036
Asante-Duah K (2002) Public health risk assessment for human exposure to chemicals. Springer, Dordrecht
ATSDR (Agency for Toxic Substances and Disease Registry) (2000) Toxicological profile for arsenic. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Atlanta, GA
Bissen M, Frimmel FH (2003) Arsenic - a review. Part I: occurrence, toxicity, speciation, mobility. Acta Hydrochim Hydrobiol 31:9–18. https://doi.org/10.1002/aheh.200390025
Canadian soil quality guidelines (1997) Canadian Council of Ministers of the Environment, Winnipeg, Canada. https://www.ccme.ca/files/Resources/supporting_scientific_documents/pn_1268_e.pdf. Accessed 1 August 2018
Dahal BM, Fuerhacker M, Mentler A, Karki K, Shrestha R, Blum W (2008) Arsenic contamination of soils and agricultural plants through irrigation water in Nepal. Environ Pollut 155:157–163. https://doi.org/10.1016/j.envpol.2007.10.024
Dai Y, Lv J, Liu K, Zhao X, Cao Y (2016) Major controlling factors and prediction models for arsenic uptake from soil to wheat plants. Ecotoxicol Environ Saf 130:256–262. https://doi.org/10.1007/s11368-014-0854-z
Environmental quality standards for soil pollution (n.d.) Ministry of the Environment, Government of Japan, Japan https://www.env.go.jp/en/water/soil/sp.html Accessed 1 August 2018
Farooq MA, Islam F, Ali B, Najeeb U, Mao B, Gill RA, Zhou W (2016) Arsenic toxicity in plants: cellular and molecular mechanisms of its transport and metabolism. Environ Exp Bot 132:42–52. https://doi.org/10.1016/j.envexpbot.2016.08.004
Gunduz O, Şimşek C, Hasözbek A (2010) Arsenic pollution in the groundwater of Simav Plain, Turkey: its impact on water quality and human health. Water Air Soil Poll 205:43–62. https://doi.org/10.1007/s11270-009-0055-3
Gunduz O, Elçi A, Şimşek C, Baba A, Bakar C, Gürleyük H (2012) Simav Ovası (Kutahya) Yeraltı Suyunda Arsenik Kirliliğinin Araştırılması ve İnsan Sağlığına Olan Risklerinin Değerlendirilmesi (Final Report). TÜBİTAK Project No 109Y029, Izmir, Turkey (in Turkish)
Gunduz O, Bakar C, Şimşek C, Baba A, Elçi A, Gürleyük H, Mutlu M, Çakır A (2015) Statistical analysis of causes of death (2005-2010) in villages of Simav Plain, Turkey, with high arsenic levels in drinking water supplies. Arch Environ Occup Health 70:35–46. https://doi.org/10.1080/19338244.2013.872076
Gunduz O, Bakar C, Şimşek C, Baba A, Elçi A, Gürleyük H, Mutlu M, Çakır A (2017) The health risk associated with chronic diseases in villages with high arsenic levels in drinking water supplies. Expos Health 9:261–273. https://doi.org/10.1007/s12403-016-0238-2
Güneş A (2010) Simav ovası (eski Simav gölü-Simav) ekolojik özellikleri. MSc Thesis, Dumlupınar University, Kutahya, Turkey (in Turkish)
ITASHY (2005) Regulation on waters intended for human consumption (Rep. No. TS 266). Official Gazette, 17 February 2005, #25730 (in Turkish)
JECFA (2010) Joint FAO/WHO Expert Committee on Food Additives, 72nd meeting, summary and conclusions. World Health Organization
Jiang Y, Zeng X, Fan X, Chao S, Zhu M, Cao H (2015) Levels of arsenic pollution in daily foodstuffs and soils and its associated human health risk in a town in Jiangsu Province, China. Ecotoxicol Environ Saf 122:198–204. https://doi.org/10.1016/j.ecoenv.2015.07.018
Jolly YN, Islam A, Akbar S (2013) Transfer of metals from soil to vegetables and possible health risk assessment. Springer Plus 2:385. https://doi.org/10.1186/2193-1801-2-385
Juhasz AL, Herde P, Herde C, Boland J, Smith E (2015) Predicting arsenic relative bioavailability using multiple in vitro assays: validation of in vivo-in vitro correlations. Environ Sci Technol 49:11167–11175. https://doi.org/10.1021/acs.est.5b02508
Kabata-Pendias A, Pendias H (2011) Trace elements in soils and plants, 4th edn. CRC Press, Washington, DC
Kar S, Das S, Jean JS, Chakraborty S, Liu CC (2013) Arsenic in the water-soil-plant system and the potential health risks in the coastal part of Chianan Plain, Southwestern Taiwan. J Asian Earth Sci 77:295–302. https://doi.org/10.1016/j.jseaes.2013.03.003
KGOPDEU (Kutahya Governor’s Office Provincial Directorate for Environment and Urbanization) (2011) Kutahya provincial environmental status report. Kutahya, Turkey (in Turkish).https://webdosya.csb.gov.tr/db/ced/editordosya/kutahya_icdr2011.pdf. Accessed 1 Aug 2018
KGOPDEU (Kutahya Governor’s Office Provincial Directorate for Environment and Urbanization) (2016) Kutahya provincial environmental status report. Kutahya Turkey (in Turkish). https://webdosya.csb.gov.tr/db/ced/editordosya/kutahya_icdr2016.pdf. Accessed 1 Aug 2018
Khan A, Khan S, Khan MA, Qamar Z, Waqas M (2015) The uptake and bioaccumulation of heavy metals by food plants, their effects on plants nutrients, and associated health risk: a review. Environ Sci Pollut Res 22:13772–13799. https://doi.org/10.1007/s11356-015-4881-0
Neidhardt H, Norra S, Tang X, Guo H, Stüben D (2012) Impact of irrigation with high arsenic burdened groundwater on the soil-plant system: results from a case study in the Inner Mongolia, China. Environ Pollut 163:8–13. https://doi.org/10.1016/j.envpol.2011.12.033
Núñez R, García MA, Alonso J, Melgar MJ (2018) Arsenic, cadmium and lead in fresh and processed tuna marketed in Galicia (NW Spain): risk assessment of dietary exposure. Sci Total Environ 627:322–331. https://doi.org/10.1016/j.scitotenv.2018.01.253
Pizarro I, Gómez-Gómez M, León J, Román D, Palacios M (2016) Bioaccessibility and arsenic speciation in carrots, beets and quinoa from a contaminated area of Chile. Sci Total Environ 565:557–563. https://doi.org/10.1016/j.scitotenv.2016.04.199
Pollution Control Department of Thailand (2001) Water quality standards. http://www.pcd.go.th/. Accessed 1 Aug 2018
Rasheed H, Kay P, Slack R, Gong YY (2018) Arsenic species in wheat, raw and cooked rice: exposure and associated health implications. Sci Total Environ 634:366–373. https://doi.org/10.1016/j.scitotenv.2018.03.339
Rehman ZU, Khan S, Qin K, Brusseau ML, Shah MT, Din I (2016) Quantification of inorganic arsenic exposure and cancer risk via consumption of vegetables in southern selected districts of Pakistan. Sci Total Environ 550:321–329. https://doi.org/10.1016/j.scitotenv.2016.01.094
Rosas-Castor JM, Guzman-Mar JL, Alfaro-Barbosa JM, Hernández-Ramírez A, Pérez-Maldonado IN, Caballero-Quintero A, Hinojosa-Reyes L (2014a) Evaluation of the transfer of soil arsenic to maize crops in suburban areas of San Luis Potosi, Mexico. Sci Total Environ 497-498:153–162. https://doi.org/10.1016/j.scitotenv.2014.07.072
Rosas-Castor JM, Guzmán-Mar JL, Hernández-Ramírez A, Garza-González MT, Hinojosa-Reyes L (2014b) Arsenic accumulation in maize crop (Zea mays): a review. Sci Total Environ 488–489:176–187. https://doi.org/10.1016/j.scitotenv.2014.04.075
Singh V, Brar MS, Sharma P, Malhi SS (2010) Arsenic in water, soil, and Rice plants in the Indo-Gangetic Plains of northwestern India. Commun Soil Sci Plant Anal 41:1350–1360. https://doi.org/10.1080/00103621003759353
Sofuoglu SC, Güzelkaya H, Akgül Ö, Kavcar P, Kurucaovalı F, Sofuoglu A (2014) Speciated arsenic concentrations, exposure, and associated health risks for rice and bulgur. Food Chem Toxicol 64:184–191. https://doi.org/10.1016/j.fct.2013.11.029
The World Bank (2017) https://data.worldbank.org/indicator/SP.DYN.LE00.IN?locations=TR&view=chart. Accessed 27 July 2018
TKKY (2001) Turkey Soil Pollution Control Regulation (Rep. No. TSP 24609). Official Gazette, Dated 10 December 2001, Numbered 24609 (in Turkish)
TSI (Turkish Statistical Institute) (2016) http://www.turkstat.gov.tr/PreTabloArama.do?metod=search. Accessed 27 July 2018
USEPA (United States Environmental Protection Agency) (2011) Exposure factors handbook 2011 edition. US Environmental Protection Agency, Washington, DC EPA/600/R09/052F
Warren GP, Alloway BJ, Lepp NW, Singh B, Bochereau FJM, Penny C (2003) Field trials to assess the uptake of arsenic by vegetables from contaminated soils and soil remediation with iron oxides. Sci Total Environ 311:19–33. https://doi.org/10.1016/S0048-9697(03)00096-2
WHO (2001) Environmental health criteria 224: arsenic and arsenic compounds. World Health Organization, Geneva
WHO (2010) Exposure to arsenic: a major public health concern. World Health Organization, Geneva
Woolson EA (1973) Arsenic phytotoxicity and uptake in six vegetable crops. Weed Sci 21:524–527
Yoon Y, Lee WM, An YJ (2015) Phytotoxicity of arsenic compounds on crop plant seedlings. Environ Sci Pollut Res 22:11047–11056. https://doi.org/10.1007/s11356-015-4317-x
Zhang H, Selim HM (2008) Reaction and transport of arsenic in soils: equilibrium and kinetic modeling. Adv Agron 98:45–115. https://doi.org/10.1016/S0065-2113(08)00202-2
Zhao FJ, Ma JF, Meharg AA, McGrath SP (2009) Arsenic uptake and metabolism in plants. New Phytol 181:777–794. https://doi.org/10.1111/j.1469-8137.2008.02716.x
Zhao FJ, McGrath SP, Meharg AA (2010) Arsenic as a food chain contaminant: mechanisms of plant uptake and metabolism and mitigation strategies. Annu Rev Plant Biol 61:535–559. https://doi.org/10.1146/annurev-arplant-042809-112152
Zhu Y-G, Williams PN, Meharg AA (2008) Exposure to inorganic arsenic from rice: a global health issue? Environ Pollut 154:169–171. https://doi.org/10.1016/j.envpol.2008.03.015
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Can-Terzi, B., Gunduz, O. & Sofuoglu, S.C. A deterministic and stochastic assessment for exposure and risk of arsenic via ingestion of edible crops. Environ Sci Pollut Res 26, 26855–26868 (2019). https://doi.org/10.1007/s11356-019-05774-y
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DOI: https://doi.org/10.1007/s11356-019-05774-y