This special issue provides creating synergies of “practice and research” increasing the potential and commercial viability of research and development in the field of Industry 4.0 paradigm, SMART technologies, intelligent manufacturing systems and applications, Lean management and manufacturing, simulation of manufacturing companies, the complexity of supply chain management, management and intelligent infrastructure (road, freight, public transport), RFID in manufacturing, wide range of ICT application challenges, communication ecosystem security, enterprise information system, traffic/transport/logistic issues in Industry 4.0.

Our goal was to create endless opportunities for collaborative networks in science, research and education and, of course, to transfer this knowledge to the academic and work environment. In the context of deepening mega-competition, science policy has a tendency to return the invested funds as quickly as possible, which is also reflected in efforts to accelerate knowledge transfer and the overall innovation process. The interdisciplinary of research is growing, resulting in the establishment of multidisciplinary research teams and workplaces.

Rapid socio-economic, scientific and technological development and computerization balanced by humanization, largely induced in developed countries by revolutionary advances in science and technology, together with deepening globalization, have also led to new trends, which are reflected in the research orientations. In general, research and development are required to answer the civilization challenges of the beginning of the new century. Naturally, these orientations also reflect the peculiarities of the respective regions, but the selected directions of scientific research are generally identical.

This issue features six selected articles of high quality. The first article, with the title “Use of BIM Technology and Impact on Productivity in Construction Project Management” is focused on building information modelling as an illustration of the physical and functional characteristics of a technology that connects project information databases in every field. This research discussed the issue of the use of BIM technology and analyses BIM effect on productivity in construction project management.

The second article “Case study: The Simulation modelling to improve the efficiency and performance of production process” provides a comprehensive result of using computer simulation to increase the efficiency and efficiency of custom production of a company. The use of simulation modelling as a scientific method in research and practice brings benefits such as financial, time, material and energy savings, as well as streamlining activities in real practice.

The third article, “Software system design for the solution of effective material layout for the needs of production and logistics” talks about the problem of research of software solutions of the efficient layout of material within a Defined space for the needs of production storage and transport. The problem relates to using knowledge with branches of logistics, layout, math and geometry for needs of research and for needs the creation of an expert system of materials layout as the software application.

The fourth article, “Roadmap to an Adaptive Assembly Line for E-Axles”, talks about achieving high quality, high variety batch size production can be quite expensive. The focus of the presented research lies in high adaptive and cognitive aspects in the assembly along with qualitative elements.

The fifth article deals with “Application of AHP Method for Project Selection in the Context of Sustainable Development” and is focused on the multi-criteria nature of decision-making in the context of sustainable development (and its economic, social and environmental criteria) is a prerequisite for the application of multi-criteria optimization methods. The article aims to present the application of the exact scenario—Analytical Hierarchical Process in the decision process.

The main aim of the sixth article with the title “Development of Retail Network on the Example of Three Regional Towns Comparison in West Slovakia” is to show the specifics of the retail network of three regional towns in the Slovak Republic—Nitra, Trnava and Žilina. Based on the comparison result, regularities of space structure formation of the retail amenities of the mentioned towns in Slovakia were identified, and their features were pointed out.

Our sincere thanks to the Editor-in-Chief, Prof. Dr. Imrich Chlamtac and European Alliance for Innovation (EAI) for their great support and guidance during the entire process. We are also thankful to the reviewers for their efforts and all suggestion and comments in reviewing tasks of the manuscripts.