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References
Mitsuboshi S, Yamada H, Nagai K, Okajima H (2015) Switching from allopurinol to febuxostat: efficacy and tolerability in hemodialysis patients. J Pharm Health Care Sci 1:28. https://doi.org/10.1186/s40780-015-0028-1
Kutoh E, Hirate M, Ikeno Y (2014) Teneligliptin as an initial therapy for newly diagnosed, drug naive subjects with type 2 diabetes. J Clin Med Res 6(4):287–294. https://doi.org/10.14740/jocmr1841e
Deacon CF (2020) Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus. Nat Rev Endocrinol 16(11):642–653. https://doi.org/10.1038/s41574-020-0399-8
Yamagishi S, Ishibashi Y, Ojima A, Sugiura T, Matsui T (2014) Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor, decreases serum uric acid levels in type 2 diabetic patients partly by suppressing xanthine oxidase activity. Int J Cardiol 176(2):550–552. https://doi.org/10.1016/j.ijcard.2014.07.023
Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T (2003) An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition. J Biol Chem 278(3):1848–1855. https://doi.org/10.1074/jbc.M208307200
Matsumoto K, Okamoto K, Ashizawa N, Nishino T (2011) FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase. J Pharmacol Exp Ther 336(1):95–103. https://doi.org/10.1124/jpet.110.174540
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Tanemoto, M., Kasai, T. & Iida, Y. Linagliptin possibly enhances the efficacy of allosteric xanthine oxidase inhibitors. Int Urol Nephrol 56, 355–356 (2024). https://doi.org/10.1007/s11255-023-03625-x
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DOI: https://doi.org/10.1007/s11255-023-03625-x