Abstract
Introduction
To evaluate the impact of a modified transurethral resection of prostate (mTURP) in patients with a history of pelvic fracture urethral injury (PFUI) status post-urethroplasty, and subsequent lower urinary tract symptoms (LUTS) refractory to medical therapy caused by benign prostatic hyperplasia (BPH).
Methods
Five patients were identified with a history of PFUI and a successful reconstruction of the urethra, who developed severe LUTS. After maximal medical therapy failed, these patients underwent a mTURP. Their continence status and voiding parameters were recorded before and after surgery.
Results
Significant improvements in both post-void residual (172 ± 137.36 mL vs. 26.6 ± 24.44 mL), p = 0.026, and International Prostatic Symptom Score (23.6 ± 4.82 vs. 7.6 ± 4.30), p = 0.002 were observed in the study. Although maximum flow rate was not statistically significant, there was an overall improvement in Qmax in all patients (8.92 ± 3.71 vs. 16.78 ± 6.44 mL/sec). Furthermore, all patients remained continent after this modified intervention.
Conclusion
Our modified TURP provides an adjunctive option in the management of severe LUTS secondary to BPH in patients with a history of PFUI urethroplasty who are refractory to medical management. In our experience, the patients experienced a lasting response with no incontinence.
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Abbreviations
- PFUI:
-
Pelvic fracture urethral injury
- BPH:
-
Benign prostatic hyperplasia
- mTURP:
-
Modified transurethral resection of prostate
- LUTS:
-
Lower urinary tract symptoms
- PVR:
-
Post-void residual
- IPSS:
-
International Prostate Symptom Score
- TRUS:
-
Transrectal ultrasound
- IPP:
-
Intravesical prostatic protrusion
- TURP:
-
Transurethral resection of prostate
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Mishra: data analysis, manuscript writing/editing, Cristina Baeza: data analysis, protocol/project management, Laura Bukavina: data analysis, manuscript writing/editing, Reynaldo G. Gómez: protocol/project management, data analysis, manuscript writing/editing.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
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Mishra, K., Baeza, C., Bukavina, L. et al. Modified transurethral resection of the prostate for the management of BPH-related refractory lower urinary tract symptoms in patients with a history of pelvic fracture urethral injury reconstruction. Int Urol Nephrol 51, 2137–2141 (2019). https://doi.org/10.1007/s11255-019-02276-1
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DOI: https://doi.org/10.1007/s11255-019-02276-1