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Synthesis and crystal structure analysis of 2-(4-methyl-2′-biphenyl)-4-amino-1,2,4-triazole-3-thiol

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Abstract

The bioactive compound 2-(4-methyl-2′-bip-henyl)-4-amino-1,2,4-triazole-3-thiol, F.W. 282.09 was synthesized, characterized by spectroscopic techniques and confirmed by X-ray crystal structure analysis. The title compound crystallizes in monoclinic class under the space group P21/c with cell parameters, a=11.273(3) Å, b=17.245(1) Å, c=7.413(1) Å, β=97.742(5)° and Z=4. The structure exhibits inter-molecular hydrogen bonding of the type N–H···S.

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Acknowledgements

The authors are grateful to Department of Science and Technology, Government of India, New Delhi for financial support under the projects DV6/15/DST/2005-06 and SP/I2/FOO/93. The CHNS data obtained from the instruments by DST-FIST and NMR Research Institute, IISC, Bangalore for the NMR spectral analysis is greatly acknowledged. One of the authors Nanjunda Swamy S. thanks CSIR, Govt. of India for the award of CSIR-Senior Research Followship.

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Authors and Affiliations

  1. Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, 570006, India

    S. Nanjunda Swamy,  Basappa, B. Prabhuswamy & Kanchugarakoppal S. Rangappa

  2. Department of Studies in Physics, University of Mysore, Manasagangotri, Mysore, 570006, India

    S. Naveen, M. A. Sridhar & Javaregowda S. Prasad

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  1. S. Nanjunda Swamy
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  2. Basappa
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  3. S. Naveen
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  4. B. Prabhuswamy
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  5. M. A. Sridhar
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  7. Kanchugarakoppal S. Rangappa
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Correspondence to Kanchugarakoppal S. Rangappa.

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Swamy, S.N., Basappa, Naveen, S. et al. Synthesis and crystal structure analysis of 2-(4-methyl-2′-biphenyl)-4-amino-1,2,4-triazole-3-thiol. Struct Chem 17, 91–95 (2006). https://doi.org/10.1007/s11224-006-9003-7

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  • DOI: https://doi.org/10.1007/s11224-006-9003-7

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